node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ESRP1 | HNRNPM | ENSBTAP00000037030 | ENSBTAP00000074476 | Epithelial splicing regulatory protein 1. | Heterogeneous nuclear ribonucleoprotein M. | 0.513 |
ESRP1 | MBNL1 | ENSBTAP00000037030 | ENSBTAP00000069445 | Epithelial splicing regulatory protein 1. | Muscleblind like splicing regulator 1. | 0.586 |
ESRP1 | PTBP1 | ENSBTAP00000037030 | ENSBTAP00000066720 | Epithelial splicing regulatory protein 1. | Polypyrimidine tract-binding protein 1; Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre- mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre- mRNA. Represses the splicing of MAPT/Tau exon 10 (By similarity). | 0.551 |
ESRP1 | QKI | ENSBTAP00000037030 | ENSBTAP00000048511 | Epithelial splicing regulatory protein 1. | Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity). | 0.744 |
ESRP1 | RBFOX2 | ENSBTAP00000037030 | ENSBTAP00000066608 | Epithelial splicing regulatory protein 1. | RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue- specific exons and of differentially spliced exons during erythropoiesis. Seems to act as a coregulatory factor of ER-alpha (By similarity). | 0.682 |
ESRP1 | RBM24 | ENSBTAP00000037030 | ENSBTAP00000038290 | Epithelial splicing regulatory protein 1. | RNA binding motif protein 24. | 0.405 |
ESRP1 | RBPMS | ENSBTAP00000037030 | ENSBTAP00000067085 | Epithelial splicing regulatory protein 1. | RNA binding protein, mRNA processing factor. | 0.455 |
HNRNPM | ESRP1 | ENSBTAP00000074476 | ENSBTAP00000037030 | Heterogeneous nuclear ribonucleoprotein M. | Epithelial splicing regulatory protein 1. | 0.513 |
HNRNPM | PTBP1 | ENSBTAP00000074476 | ENSBTAP00000066720 | Heterogeneous nuclear ribonucleoprotein M. | Polypyrimidine tract-binding protein 1; Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre- mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre- mRNA. Represses the splicing of MAPT/Tau exon 10 (By similarity). | 0.872 |
HNRNPM | PTBP2 | ENSBTAP00000074476 | ENSBTAP00000071225 | Heterogeneous nuclear ribonucleoprotein M. | Polypyrimidine tract binding protein 2. | 0.473 |
HNRNPM | QKI | ENSBTAP00000074476 | ENSBTAP00000048511 | Heterogeneous nuclear ribonucleoprotein M. | Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity). | 0.555 |
HNRNPM | RBFOX2 | ENSBTAP00000074476 | ENSBTAP00000066608 | Heterogeneous nuclear ribonucleoprotein M. | RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue- specific exons and of differentially spliced exons during erythropoiesis. Seems to act as a coregulatory factor of ER-alpha (By similarity). | 0.691 |
MBNL1 | ESRP1 | ENSBTAP00000069445 | ENSBTAP00000037030 | Muscleblind like splicing regulator 1. | Epithelial splicing regulatory protein 1. | 0.586 |
MBNL1 | NOVA1 | ENSBTAP00000069445 | ENSBTAP00000071829 | Muscleblind like splicing regulator 1. | NOVA alternative splicing regulator 1. | 0.613 |
MBNL1 | PTBP1 | ENSBTAP00000069445 | ENSBTAP00000066720 | Muscleblind like splicing regulator 1. | Polypyrimidine tract-binding protein 1; Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre- mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre- mRNA. Represses the splicing of MAPT/Tau exon 10 (By similarity). | 0.562 |
MBNL1 | PTBP2 | ENSBTAP00000069445 | ENSBTAP00000071225 | Muscleblind like splicing regulator 1. | Polypyrimidine tract binding protein 2. | 0.525 |
MBNL1 | QKI | ENSBTAP00000069445 | ENSBTAP00000048511 | Muscleblind like splicing regulator 1. | Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity). | 0.737 |
MBNL1 | RBFOX2 | ENSBTAP00000069445 | ENSBTAP00000066608 | Muscleblind like splicing regulator 1. | RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue- specific exons and of differentially spliced exons during erythropoiesis. Seems to act as a coregulatory factor of ER-alpha (By similarity). | 0.711 |
MBNL1 | RBM24 | ENSBTAP00000069445 | ENSBTAP00000038290 | Muscleblind like splicing regulator 1. | RNA binding motif protein 24. | 0.569 |
MBNL1 | RBM38 | ENSBTAP00000069445 | ENSBTAP00000010660 | Muscleblind like splicing regulator 1. | RNA binding motif protein 38. | 0.449 |