STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GATA5Transcription factor GATA-5; Transcription factor required during cardiovascular development. Plays an important role in the transcriptional program(s) that underlies smooth muscle cell diversity. Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer (By similarity). (403 aa)    
Predicted Functional Partners:
NKX2-5
NK2 transcription factor related, locus 5 (Drosophila).
   
 
 0.859
TBX20
T-box transcription factor 20.
   
 
 0.732
ZFPM2
Zinc finger protein, FOG family member 2.
    
 0.717
TBX5
T-box transcription factor 5.
   
 
 0.709
ZFPM1
Zinc finger protein, FOG family member 1.
   
 0.687
FOXA1
Forkhead box A1.
   
 
 0.676
HAND2
Heart and neural crest derivatives expressed 2.
   
 
 0.624
LMO2
Rhombotin-2; Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.
    
 
 0.571
ISL1
ISL LIM homeobox 1.
    
 
 0.542
GATA6
GATA binding protein 6.
  
 
0.531
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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