| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CEBPB | CIITA | ENSBTAP00000073202 | ENSBTAP00000027518 | CCAAT/enhancer-binding protein beta; Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Plays also a significant role in adipogenesis, as well as in the gluconeogenic pathway, liver regeneration, and hematopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Its functional capacity is governed by protein interactions and post-translational protein modifications. During early embryogenesis, plays essential and redundant functions with CEBPA. Has a promitotic effect on many cell types such as hepatocytes and adipo [...] | Class II major histocompatibility complex transactivator. | 0.924 |
| CEBPB | CREB1 | ENSBTAP00000073202 | ENSBTAP00000007201 | CCAAT/enhancer-binding protein beta; Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Plays also a significant role in adipogenesis, as well as in the gluconeogenic pathway, liver regeneration, and hematopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Its functional capacity is governed by protein interactions and post-translational protein modifications. During early embryogenesis, plays essential and redundant functions with CEBPA. Has a promitotic effect on many cell types such as hepatocytes and adipo [...] | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | 0.679 |
| CEBPB | STAT1 | ENSBTAP00000073202 | ENSBTAP00000067158 | CCAAT/enhancer-binding protein beta; Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Plays also a significant role in adipogenesis, as well as in the gluconeogenic pathway, liver regeneration, and hematopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Its functional capacity is governed by protein interactions and post-translational protein modifications. During early embryogenesis, plays essential and redundant functions with CEBPA. Has a promitotic effect on many cell types such as hepatocytes and adipo [...] | Signal transducer and activator of transcription. | 0.698 |
| CEBPB | STAT4 | ENSBTAP00000073202 | ENSBTAP00000030561 | CCAAT/enhancer-binding protein beta; Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Plays also a significant role in adipogenesis, as well as in the gluconeogenic pathway, liver regeneration, and hematopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Its functional capacity is governed by protein interactions and post-translational protein modifications. During early embryogenesis, plays essential and redundant functions with CEBPA. Has a promitotic effect on many cell types such as hepatocytes and adipo [...] | Signal transducer and activator of transcription. | 0.570 |
| CIITA | CEBPB | ENSBTAP00000027518 | ENSBTAP00000073202 | Class II major histocompatibility complex transactivator. | CCAAT/enhancer-binding protein beta; Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Plays also a significant role in adipogenesis, as well as in the gluconeogenic pathway, liver regeneration, and hematopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Its functional capacity is governed by protein interactions and post-translational protein modifications. During early embryogenesis, plays essential and redundant functions with CEBPA. Has a promitotic effect on many cell types such as hepatocytes and adipo [...] | 0.924 |
| CIITA | CREB1 | ENSBTAP00000027518 | ENSBTAP00000007201 | Class II major histocompatibility complex transactivator. | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | 0.939 |
| CIITA | NFYA | ENSBTAP00000027518 | ENSBTAP00000013080 | Class II major histocompatibility complex transactivator. | Nuclear transcription factor Y subunit alpha; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1 (By similarity). | 0.937 |
| CIITA | NFYB | ENSBTAP00000027518 | ENSBTAP00000041024 | Class II major histocompatibility complex transactivator. | Nuclear transcription factor Y subunit beta; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors (By similarity). | 0.812 |
| CIITA | NFYC | ENSBTAP00000027518 | ENSBTAP00000067634 | Class II major histocompatibility complex transactivator. | Nuclear transcription factor Y subunit gamma; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors (By similarity). | 0.937 |
| CIITA | RFX5 | ENSBTAP00000027518 | ENSBTAP00000064861 | Class II major histocompatibility complex transactivator. | Regulatory factor X5. | 0.997 |
| CIITA | RFXANK | ENSBTAP00000027518 | ENSBTAP00000070348 | Class II major histocompatibility complex transactivator. | Regulatory factor X associated ankyrin containing protein. | 0.992 |
| CIITA | RFXAP | ENSBTAP00000027518 | ENSBTAP00000007033 | Class II major histocompatibility complex transactivator. | Regulatory factor X associated protein. | 0.983 |
| CIITA | STAT1 | ENSBTAP00000027518 | ENSBTAP00000067158 | Class II major histocompatibility complex transactivator. | Signal transducer and activator of transcription. | 0.976 |
| CIITA | STAT4 | ENSBTAP00000027518 | ENSBTAP00000030561 | Class II major histocompatibility complex transactivator. | Signal transducer and activator of transcription. | 0.817 |
| CREB1 | CEBPB | ENSBTAP00000007201 | ENSBTAP00000073202 | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | CCAAT/enhancer-binding protein beta; Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Plays also a significant role in adipogenesis, as well as in the gluconeogenic pathway, liver regeneration, and hematopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Its functional capacity is governed by protein interactions and post-translational protein modifications. During early embryogenesis, plays essential and redundant functions with CEBPA. Has a promitotic effect on many cell types such as hepatocytes and adipo [...] | 0.679 |
| CREB1 | CIITA | ENSBTAP00000007201 | ENSBTAP00000027518 | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | Class II major histocompatibility complex transactivator. | 0.939 |
| CREB1 | NFYA | ENSBTAP00000007201 | ENSBTAP00000013080 | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | Nuclear transcription factor Y subunit alpha; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1 (By similarity). | 0.481 |
| CREB1 | RFX5 | ENSBTAP00000007201 | ENSBTAP00000064861 | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | Regulatory factor X5. | 0.498 |
| CREB1 | STAT1 | ENSBTAP00000007201 | ENSBTAP00000067158 | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | Signal transducer and activator of transcription. | 0.657 |
| CREB1 | STAT4 | ENSBTAP00000007201 | ENSBTAP00000030561 | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | Signal transducer and activator of transcription. | 0.508 |
