STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHAMP1Chromosome alignment maintaining phosphoprotein 1. (804 aa)    
Predicted Functional Partners:
SAYSD1
SAYSvFN domain-containing protein 1.
      
 0.740
PSD4
Pleckstrin and Sec7 domain containing 4.
      
 0.728
NSL1
NSL1 component of MIS12 kinetochore complex.
    
 
 0.705
TPGS2
Tubulin polyglutamylase complex subunit 2.
      
 0.685
MAD2L2
Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...]
    
 
 0.673
SAC3D1
SAC3 domain containing 1.
      
 0.665
TRMT13
tRNA methyltransferase 13 homolog.
      
 0.662
ERLIN1
ER lipid raft associated 1.
      
 0.641
POGZ
Pogo transposable element derived with ZNF domain.
   
 
 0.618
REPS1
RALBP1 associated Eps domain containing 1.
   
  
 0.585
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.