STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRASPGeneral receptor for phosphoinositides 1 associated scaffold protein. (394 aa)    
Predicted Functional Partners:
CYTH2
Cytohesin-2; Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (By similarity). Involved in neurite growth (By similarity).
   
 
 0.787
ACTL9
Actin-like protein 9.
    
 
 0.662
DLGAP3
DLG associated protein 3.
  
 
 
 0.618
GPRASP1
Uncharacterized protein.
    
 
 0.521
OPN5
Opsin 5; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.495
CLYBL
Citrate lyase beta like.
    
 
 0.481
DOCK3
Dedicator of cytokinesis 3; Belongs to the DOCK family.
    
 
 0.478
DOCK5
Dedicator of cytokinesis 5; Belongs to the DOCK family.
    
 
 0.475
CYTH3
Cytohesin 3.
    
 
 0.472
DOCK2
Dedicator of cytokinesis 2; Belongs to the DOCK family.
    
 
 0.470
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.