| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDC42 | KALRN | ENSBTAP00000059852 | ENSBTAP00000032241 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Kalirin RhoGEF kinase. | 0.727 |
| CDC42 | RHOG | ENSBTAP00000059852 | ENSBTAP00000000453 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Ras homolog gene family, member G (Rho G). | 0.613 |
| CDC42 | SHANK3 | ENSBTAP00000059852 | ENSBTAP00000023459 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | SH3 and multiple ankyrin repeat domains 3. | 0.568 |
| CDC42 | TIAM1-2 | ENSBTAP00000059852 | ENSBTAP00000054169 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | T cell lymphoma invasion and metastasis 1. | 0.961 |
| DAPK2 | KALRN | ENSBTAP00000015689 | ENSBTAP00000032241 | Death associated protein kinase 2. | Kalirin RhoGEF kinase. | 0.844 |
| DAPK3 | KALRN | ENSBTAP00000027209 | ENSBTAP00000032241 | Death associated protein kinase 3; Belongs to the protein kinase superfamily. | Kalirin RhoGEF kinase. | 0.880 |
| DISC1 | KALRN | ENSBTAP00000066138 | ENSBTAP00000032241 | DISC1 scaffold protein. | Kalirin RhoGEF kinase. | 0.697 |
| DLG4 | KALRN | ENSBTAP00000003326 | ENSBTAP00000032241 | Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. | Kalirin RhoGEF kinase. | 0.764 |
| DLG4 | SHANK3 | ENSBTAP00000003326 | ENSBTAP00000023459 | Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. | SH3 and multiple ankyrin repeat domains 3. | 0.832 |
| DLG4 | SYNGAP1 | ENSBTAP00000003326 | ENSBTAP00000027936 | Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. | Synaptic Ras GTPase activating protein 1. | 0.898 |
| KALRN | CDC42 | ENSBTAP00000032241 | ENSBTAP00000059852 | Kalirin RhoGEF kinase. | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | 0.727 |
| KALRN | DAPK2 | ENSBTAP00000032241 | ENSBTAP00000015689 | Kalirin RhoGEF kinase. | Death associated protein kinase 2. | 0.844 |
| KALRN | DAPK3 | ENSBTAP00000032241 | ENSBTAP00000027209 | Kalirin RhoGEF kinase. | Death associated protein kinase 3; Belongs to the protein kinase superfamily. | 0.880 |
| KALRN | DISC1 | ENSBTAP00000032241 | ENSBTAP00000066138 | Kalirin RhoGEF kinase. | DISC1 scaffold protein. | 0.697 |
| KALRN | DLG4 | ENSBTAP00000032241 | ENSBTAP00000003326 | Kalirin RhoGEF kinase. | Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. | 0.764 |
| KALRN | PAM | ENSBTAP00000032241 | ENSBTAP00000016466 | Kalirin RhoGEF kinase. | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase; Bifunctional enzyme that catalyzes the post-translational modification of inactive peptidylglycine precursors to the corresponding bioactive alpha-amidated peptides, a terminal modification in biosynthesis of many neural and endocrine peptides. Alpha-amidation involves two sequential reactions, both of which are catalyzed by separate catalytic domains of the enzyme. The first step, catalyzed by peptidyl alpha-hydroxylating monoxygenase (PHM) domain, is the copper-, ascorbate-, and O2- dependent stereospecific hydroxylation (with S st [...] | 0.682 |
| KALRN | RHOG | ENSBTAP00000032241 | ENSBTAP00000000453 | Kalirin RhoGEF kinase. | Ras homolog gene family, member G (Rho G). | 0.748 |
| KALRN | SHANK3 | ENSBTAP00000032241 | ENSBTAP00000023459 | Kalirin RhoGEF kinase. | SH3 and multiple ankyrin repeat domains 3. | 0.740 |
| KALRN | SYNGAP1 | ENSBTAP00000032241 | ENSBTAP00000027936 | Kalirin RhoGEF kinase. | Synaptic Ras GTPase activating protein 1. | 0.771 |
| KALRN | TIAM1-2 | ENSBTAP00000032241 | ENSBTAP00000054169 | Kalirin RhoGEF kinase. | T cell lymphoma invasion and metastasis 1. | 0.720 |
