node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SLC22A1 | SLC22A2 | ENSBTAP00000004059 | ENSBTAP00000012607 | Solute carrier family 22 member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1- methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1- methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N- methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA recepto [...] | Solute carrier family 22 member 2. | 0.913 |
SLC22A1 | SLC22A3 | ENSBTAP00000004059 | ENSBTAP00000011256 | Solute carrier family 22 member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1- methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1- methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N- methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA recepto [...] | Solute carrier family 22 member 3. | 0.912 |
SLC22A1 | SLC22A4 | ENSBTAP00000004059 | ENSBTAP00000013203 | Solute carrier family 22 member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1- methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1- methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N- methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA recepto [...] | Solute carrier family 22 member 4. | 0.931 |
SLC22A1 | SLC22A5 | ENSBTAP00000004059 | ENSBTAP00000035601 | Solute carrier family 22 member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1- methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1- methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N- methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA recepto [...] | Solute carrier family 22 (Organic cation/carnitine transporter), member 5. | 0.930 |
SLC22A1 | SLC44A1 | ENSBTAP00000004059 | ENSBTAP00000009435 | Solute carrier family 22 member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1- methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1- methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N- methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA recepto [...] | Solute carrier family 44 member 1; Belongs to the CTL (choline transporter-like) family. | 0.934 |
SLC22A1 | SLC44A2 | ENSBTAP00000004059 | ENSBTAP00000067400 | Solute carrier family 22 member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1- methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1- methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N- methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA recepto [...] | Choline transporter-like protein 2; Choline transporter; Belongs to the CTL (choline transporter-like) family. | 0.948 |
SLC22A1 | SLC44A3 | ENSBTAP00000004059 | ENSBTAP00000063549 | Solute carrier family 22 member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1- methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1- methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N- methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA recepto [...] | Choline transporter-like protein 3. | 0.934 |
SLC22A1 | SLC44A4 | ENSBTAP00000004059 | ENSBTAP00000042762 | Solute carrier family 22 member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1- methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1- methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N- methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA recepto [...] | Choline transporter-like protein 4; Choline transporter that plays a role in the choline- acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury (By similarity). Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis (By similarity). | 0.941 |
SLC22A1 | SLC5A7 | ENSBTAP00000004059 | ENSBTAP00000005693 | Solute carrier family 22 member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1- methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1- methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N- methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA recepto [...] | Solute carrier family 5 (Choline transporter), member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.936 |
SLC22A2 | SLC22A1 | ENSBTAP00000012607 | ENSBTAP00000004059 | Solute carrier family 22 member 2. | Solute carrier family 22 member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1- methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1- methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N- methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA recepto [...] | 0.913 |
SLC22A2 | SLC22A3 | ENSBTAP00000012607 | ENSBTAP00000011256 | Solute carrier family 22 member 2. | Solute carrier family 22 member 3. | 0.911 |
SLC22A2 | SLC22A4 | ENSBTAP00000012607 | ENSBTAP00000013203 | Solute carrier family 22 member 2. | Solute carrier family 22 member 4. | 0.932 |
SLC22A2 | SLC22A5 | ENSBTAP00000012607 | ENSBTAP00000035601 | Solute carrier family 22 member 2. | Solute carrier family 22 (Organic cation/carnitine transporter), member 5. | 0.932 |
SLC22A2 | SLC44A1 | ENSBTAP00000012607 | ENSBTAP00000009435 | Solute carrier family 22 member 2. | Solute carrier family 44 member 1; Belongs to the CTL (choline transporter-like) family. | 0.932 |
SLC22A2 | SLC44A2 | ENSBTAP00000012607 | ENSBTAP00000067400 | Solute carrier family 22 member 2. | Choline transporter-like protein 2; Choline transporter; Belongs to the CTL (choline transporter-like) family. | 0.913 |
SLC22A2 | SLC44A3 | ENSBTAP00000012607 | ENSBTAP00000063549 | Solute carrier family 22 member 2. | Choline transporter-like protein 3. | 0.904 |
SLC22A2 | SLC44A4 | ENSBTAP00000012607 | ENSBTAP00000042762 | Solute carrier family 22 member 2. | Choline transporter-like protein 4; Choline transporter that plays a role in the choline- acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury (By similarity). Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis (By similarity). | 0.936 |
SLC22A2 | SLC5A7 | ENSBTAP00000012607 | ENSBTAP00000005693 | Solute carrier family 22 member 2. | Solute carrier family 5 (Choline transporter), member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.932 |
SLC22A3 | SLC22A1 | ENSBTAP00000011256 | ENSBTAP00000004059 | Solute carrier family 22 member 3. | Solute carrier family 22 member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1- methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1- methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N- methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA recepto [...] | 0.912 |
SLC22A3 | SLC22A2 | ENSBTAP00000011256 | ENSBTAP00000012607 | Solute carrier family 22 member 3. | Solute carrier family 22 member 2. | 0.911 |