| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CHD4 | TAF1A | ENSBTAP00000019612 | ENSBTAP00000017928 | Chromodomain helicase DNA binding protein 4. | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa. | 0.506 |
| CHD4 | TAF1B | ENSBTAP00000019612 | ENSBTAP00000041230 | Chromodomain helicase DNA binding protein 4. | TATA box-binding protein-associated factor RNA polymerase I subunit B; Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3 (By similarity). Belongs to the RRN7/TAF1B family. | 0.492 |
| CHD4 | TAF1C | ENSBTAP00000019612 | ENSBTAP00000051454 | Chromodomain helicase DNA binding protein 4. | TATA-box binding protein associated factor, RNA polymerase I subunit C. | 0.471 |
| CHD4 | TAF1D | ENSBTAP00000019612 | ENSBTAP00000004611 | Chromodomain helicase DNA binding protein 4. | TATA box-binding protein-associated factor RNA polymerase I subunit D; Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits (By similarity). | 0.458 |
| CHD4 | UBTF | ENSBTAP00000019612 | ENSBTAP00000034691 | Chromodomain helicase DNA binding protein 4. | Upstream binding transcription factor. | 0.816 |
| MAPK3 | UBTF | ENSBTAP00000021507 | ENSBTAP00000034691 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Upstream binding transcription factor. | 0.774 |
| POLR1A | POLR1B | ENSBTAP00000008496 | ENSBTAP00000018830 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| POLR1A | POLR1E | ENSBTAP00000008496 | ENSBTAP00000016250 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Polymerase (RNA) I polypeptide E, 53kDa. | 0.999 |
| POLR1A | RRN3 | ENSBTAP00000008496 | ENSBTAP00000006308 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Uncharacterized protein. | 0.989 |
| POLR1A | TAF1A | ENSBTAP00000008496 | ENSBTAP00000017928 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa. | 0.846 |
| POLR1A | TAF1B | ENSBTAP00000008496 | ENSBTAP00000041230 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | TATA box-binding protein-associated factor RNA polymerase I subunit B; Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3 (By similarity). Belongs to the RRN7/TAF1B family. | 0.809 |
| POLR1A | TAF1C | ENSBTAP00000008496 | ENSBTAP00000051454 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | TATA-box binding protein associated factor, RNA polymerase I subunit C. | 0.686 |
| POLR1A | TAF1D | ENSBTAP00000008496 | ENSBTAP00000004611 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | TATA box-binding protein-associated factor RNA polymerase I subunit D; Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits (By similarity). | 0.749 |
| POLR1A | UBTF | ENSBTAP00000008496 | ENSBTAP00000034691 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Upstream binding transcription factor. | 0.941 |
| POLR1B | POLR1A | ENSBTAP00000018830 | ENSBTAP00000008496 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| POLR1B | POLR1E | ENSBTAP00000018830 | ENSBTAP00000016250 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Polymerase (RNA) I polypeptide E, 53kDa. | 0.997 |
| POLR1B | RRN3 | ENSBTAP00000018830 | ENSBTAP00000006308 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Uncharacterized protein. | 0.978 |
| POLR1B | TAF1A | ENSBTAP00000018830 | ENSBTAP00000017928 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa. | 0.793 |
| POLR1B | TAF1B | ENSBTAP00000018830 | ENSBTAP00000041230 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | TATA box-binding protein-associated factor RNA polymerase I subunit B; Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3 (By similarity). Belongs to the RRN7/TAF1B family. | 0.712 |
| POLR1B | TAF1C | ENSBTAP00000018830 | ENSBTAP00000051454 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | TATA-box binding protein associated factor, RNA polymerase I subunit C. | 0.724 |
