node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFF1 | AFF4 | ENSBTAP00000069534 | ENSBTAP00000012480 | AF4/FMR2 family member 1. | AF4/FMR2 family member 4. | 0.961 |
AFF1 | BRD4 | ENSBTAP00000069534 | ENSBTAP00000070106 | AF4/FMR2 family member 1. | Bromodomain containing 4. | 0.639 |
AFF1 | CCNK | ENSBTAP00000069534 | ENSBTAP00000055600 | AF4/FMR2 family member 1. | Cyclin K; Belongs to the cyclin family. | 0.661 |
AFF1 | CCNT1 | ENSBTAP00000069534 | ENSBTAP00000007703 | AF4/FMR2 family member 1. | Cyclin-T1; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C- terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). | 0.968 |
AFF1 | CCNT2 | ENSBTAP00000069534 | ENSBTAP00000067058 | AF4/FMR2 family member 1. | Cyclin T2; Belongs to the cyclin family. | 0.939 |
AFF1 | CDK9 | ENSBTAP00000069534 | ENSBTAP00000006162 | AF4/FMR2 family member 1. | Cyclin-dependent kinase 9; Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR and the negative elongation factors DSIF and NELF. Regulates cytoki [...] | 0.967 |
AFF1 | HEXIM2 | ENSBTAP00000069534 | ENSBTAP00000073035 | AF4/FMR2 family member 1. | Protein HEXIM2; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (By similarity); Belongs to the HEXIM family. | 0.578 |
AFF1 | LARP7 | ENSBTAP00000069534 | ENSBTAP00000061840 | AF4/FMR2 family member 1. | La ribonucleoprotein domain family member 7. | 0.680 |
AFF1 | MEPCE | ENSBTAP00000069534 | ENSBTAP00000022290 | AF4/FMR2 family member 1. | Bin3-type SAM domain-containing protein. | 0.695 |
AFF4 | AFF1 | ENSBTAP00000012480 | ENSBTAP00000069534 | AF4/FMR2 family member 4. | AF4/FMR2 family member 1. | 0.961 |
AFF4 | BRD4 | ENSBTAP00000012480 | ENSBTAP00000070106 | AF4/FMR2 family member 4. | Bromodomain containing 4. | 0.642 |
AFF4 | CCNK | ENSBTAP00000012480 | ENSBTAP00000055600 | AF4/FMR2 family member 4. | Cyclin K; Belongs to the cyclin family. | 0.733 |
AFF4 | CCNT1 | ENSBTAP00000012480 | ENSBTAP00000007703 | AF4/FMR2 family member 4. | Cyclin-T1; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (C- terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). | 0.998 |
AFF4 | CCNT2 | ENSBTAP00000012480 | ENSBTAP00000067058 | AF4/FMR2 family member 4. | Cyclin T2; Belongs to the cyclin family. | 0.968 |
AFF4 | CDK9 | ENSBTAP00000012480 | ENSBTAP00000006162 | AF4/FMR2 family member 4. | Cyclin-dependent kinase 9; Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR and the negative elongation factors DSIF and NELF. Regulates cytoki [...] | 0.995 |
AFF4 | HEXIM2 | ENSBTAP00000012480 | ENSBTAP00000073035 | AF4/FMR2 family member 4. | Protein HEXIM2; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (By similarity); Belongs to the HEXIM family. | 0.643 |
AFF4 | LARP7 | ENSBTAP00000012480 | ENSBTAP00000061840 | AF4/FMR2 family member 4. | La ribonucleoprotein domain family member 7. | 0.749 |
AFF4 | MEPCE | ENSBTAP00000012480 | ENSBTAP00000022290 | AF4/FMR2 family member 4. | Bin3-type SAM domain-containing protein. | 0.691 |
BRD4 | AFF1 | ENSBTAP00000070106 | ENSBTAP00000069534 | Bromodomain containing 4. | AF4/FMR2 family member 1. | 0.639 |
BRD4 | AFF4 | ENSBTAP00000070106 | ENSBTAP00000012480 | Bromodomain containing 4. | AF4/FMR2 family member 4. | 0.642 |