| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MEF2B | MEF2C | ENSBTAP00000002377 | ENSBTAP00000034894 | Myocyte enhancer factor 2B. | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] | 0.703 |
| MEF2B | MYF5 | ENSBTAP00000002377 | ENSBTAP00000038425 | Myocyte enhancer factor 2B. | Myogenic factor 5; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). | 0.802 |
| MEF2B | MYF6 | ENSBTAP00000002377 | ENSBTAP00000066173 | Myocyte enhancer factor 2B. | Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). | 0.806 |
| MEF2B | TCF12 | ENSBTAP00000002377 | ENSBTAP00000035793 | Myocyte enhancer factor 2B. | Transcription factor 12. | 0.607 |
| MEF2B | TCF3 | ENSBTAP00000002377 | ENSBTAP00000057296 | Myocyte enhancer factor 2B. | Transcription factor 3. | 0.551 |
| MEF2B | TCF4 | ENSBTAP00000002377 | ENSBTAP00000060741 | Myocyte enhancer factor 2B. | Transcription factor 4. | 0.525 |
| MEF2C | MEF2B | ENSBTAP00000034894 | ENSBTAP00000002377 | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] | Myocyte enhancer factor 2B. | 0.703 |
| MEF2C | MSTN | ENSBTAP00000034894 | ENSBTAP00000015674 | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] | Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth. | 0.550 |
| MEF2C | MYF5 | ENSBTAP00000034894 | ENSBTAP00000038425 | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] | Myogenic factor 5; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). | 0.865 |
| MEF2C | MYF6 | ENSBTAP00000034894 | ENSBTAP00000066173 | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] | Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). | 0.845 |
| MEF2C | MYH3 | ENSBTAP00000034894 | ENSBTAP00000001120 | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] | Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.517 |
| MEF2C | PAX3 | ENSBTAP00000034894 | ENSBTAP00000013131 | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] | Paired box 3. | 0.608 |
| MEF2C | PAX7 | ENSBTAP00000034894 | ENSBTAP00000019924 | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] | Paired box 7. | 0.669 |
| MEF2C | TCF12 | ENSBTAP00000034894 | ENSBTAP00000035793 | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] | Transcription factor 12. | 0.628 |
| MEF2C | TCF3 | ENSBTAP00000034894 | ENSBTAP00000057296 | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] | Transcription factor 3. | 0.583 |
| MEF2C | TCF4 | ENSBTAP00000034894 | ENSBTAP00000060741 | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] | Transcription factor 4. | 0.640 |
| MSTN | MEF2C | ENSBTAP00000015674 | ENSBTAP00000034894 | Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth. | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] | 0.550 |
| MSTN | MYF5 | ENSBTAP00000015674 | ENSBTAP00000038425 | Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth. | Myogenic factor 5; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). | 0.913 |
| MSTN | MYF6 | ENSBTAP00000015674 | ENSBTAP00000066173 | Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth. | Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). | 0.778 |
| MSTN | MYH3 | ENSBTAP00000015674 | ENSBTAP00000001120 | Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth. | Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.521 |
STRING v12.5 is now available!
