STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRSS57Serine protease 57; Belongs to the peptidase S1 family. (283 aa)    
Predicted Functional Partners:
HIGD2A
HIG1 domain family, member 2A.
      
 0.713
PPP1R27
Protein phosphatase 1 regulatory subunit 27.
    
 
 0.694
CCM2
CCM2 scaffold protein.
    
 
 0.628
MYO1G
Myosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.603
SPINK2B
Serine peptidase inhibitor, Kazal type 2 (Acrosin-trypsin inhibitor).
      
 0.590
CBFA2T3
CBFA2/RUNX1 partner transcriptional co-repressor 3.
    
 
 0.590
VPREB1-2
Ig-like domain-containing protein.
    
 
 0.558
MAP3K3
Mitogen-activated protein kinase kinase kinase 3.
    
 
 0.554
OR2W3
Olfactory receptor.
    
 
 0.520
MILR1
Mast cell immunoglobulin like receptor 1.
   
 
 0.518
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.