STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITLN2-2Fibrinogen C-terminal domain-containing protein. (323 aa)    
Predicted Functional Partners:
LTF
Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactoferricin B is an antimicrobial peptide. Inhibits the growth of Gram-negative and Gram-positive bacteria.
      
 0.584
IFI27L2
Interferon alpha-inducible protein 27-like protein 2; Plays a role in the apoptotic process and has a pro-apoptotic activity; Belongs to the IFI6/IFI27 family.
    
 
 0.573
ABCA13
ATP binding cassette subfamily A member 13.
    
 
 0.556
BPIFA2A
Short palate, lung and nasal epithelium carcinoma-associated protein 2A; Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
      
 0.520
IGSF23
Immunoglobulin superfamily member 23.
    
 
 0.494
CGN1
Conglutinin; Calcium-dependent lectin-like protein which binds to a yeast cell wall extract and immune complexes through the complement component (C3bi). It is capable of binding non-reducing terminal N- acetylglucosamine, mannose, and fucose residues.
   
  
 0.483
VWCE
Von Willebrand factor C and EGF domains.
      
 0.482
KLHL25
Kelch like family member 25.
      
 0.482
CLCA1
Chloride channel accessory 1.
   
 
 0.476
RGS9
Regulator of G-protein signaling 9; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to GNAT1. Involved in phototransduction; key element in the recovery phase of visual transduction.
      
 0.453
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.