STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB6Zinc finger and BTB domain-containing protein 6; May be involved in transcriptional regulation. (436 aa)    
Predicted Functional Partners:
KLHL18
Kelch like family member 18.
    
 
 0.818
KCTD2
Potassium channel tetramerization domain containing 2.
    
 
 0.815
BTBD7
BTB domain containing 7.
   
  
 0.801
ZSCAN9
Zinc finger and SCAN domain containing 9.
      
 0.740
ANKFY1
Ankyrin repeat and FYVE domain containing 1.
    
 
 0.722
RNF39
Ring finger protein 39.
    
 
 0.677
RNF186
E3 ubiquitin-protein ligase RNF186; E3 ubiquitin protein ligase that is part of an apoptotic signaling pathway activated by endoplasmic reticulum stress. In that process, stimulates the expression of proteins specific of the unfolded protein response (UPR), ubiquitinates BNIP1 and regulates its localization to the mitochondrion and induces calcium release from the endoplasmic reticulum that ultimately leads to cell apoptosis.
    
 
 0.646
SPOPL
Speckle type BTB/POZ protein like.
   
 
 0.595
RFX7
Regulatory factor X7.
   
 
 0.591
KLHL10
Kelch like family member 10.
    
 
 0.588
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.