node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTR1A | ACTR1B | ENSBTAP00000028053 | ENSBTAP00000059768 | Actin related protein 1A. | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (By similarity); Belongs to the actin family. ARP1 subfamily. | 0.901 |
ACTR1A | CAPZA1 | ENSBTAP00000028053 | ENSBTAP00000056906 | Actin related protein 1A. | F-actin-capping protein subunit alpha-1; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions. | 0.982 |
ACTR1A | CAPZA2 | ENSBTAP00000028053 | ENSBTAP00000065455 | Actin related protein 1A. | F-actin-capping protein subunit alpha-2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). | 0.865 |
ACTR1A | CAPZA3 | ENSBTAP00000028053 | ENSBTAP00000017578 | Actin related protein 1A. | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. | 0.765 |
ACTR1A | CAPZB | ENSBTAP00000028053 | ENSBTAP00000059505 | Actin related protein 1A. | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. The isoform beta-3 may play a role in spermatogenesis. Alternatively, may play a role in later maturation steps such as capacitation and fertilization which involve changes of membrane domains. May play a role in the regulation of cell morphology and cytoskeletal organization. | 0.987 |
ACTR1A | DCTN1 | ENSBTAP00000028053 | ENSBTAP00000064894 | Actin related protein 1A. | Dynactin subunit 1. | 0.997 |
ACTR1A | DCTN2 | ENSBTAP00000028053 | ENSBTAP00000066387 | Actin related protein 1A. | Dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development (By similarity). | 0.998 |
ACTR1A | DCTN4 | ENSBTAP00000028053 | ENSBTAP00000020755 | Actin related protein 1A. | Dynactin subunit 4. | 0.996 |
ACTR1A | DCTN6 | ENSBTAP00000028053 | ENSBTAP00000000989 | Actin related protein 1A. | Dynactin subunit 6. | 0.996 |
ACTR1B | ACTR1A | ENSBTAP00000059768 | ENSBTAP00000028053 | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (By similarity); Belongs to the actin family. ARP1 subfamily. | Actin related protein 1A. | 0.901 |
ACTR1B | CAPZA1 | ENSBTAP00000059768 | ENSBTAP00000056906 | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (By similarity); Belongs to the actin family. ARP1 subfamily. | F-actin-capping protein subunit alpha-1; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions. | 0.988 |
ACTR1B | CAPZA2 | ENSBTAP00000059768 | ENSBTAP00000065455 | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (By similarity); Belongs to the actin family. ARP1 subfamily. | F-actin-capping protein subunit alpha-2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). | 0.838 |
ACTR1B | CAPZA3 | ENSBTAP00000059768 | ENSBTAP00000017578 | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (By similarity); Belongs to the actin family. ARP1 subfamily. | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. | 0.549 |
ACTR1B | CAPZB | ENSBTAP00000059768 | ENSBTAP00000059505 | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (By similarity); Belongs to the actin family. ARP1 subfamily. | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. The isoform beta-3 may play a role in spermatogenesis. Alternatively, may play a role in later maturation steps such as capacitation and fertilization which involve changes of membrane domains. May play a role in the regulation of cell morphology and cytoskeletal organization. | 0.991 |
ACTR1B | DCTN1 | ENSBTAP00000059768 | ENSBTAP00000064894 | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (By similarity); Belongs to the actin family. ARP1 subfamily. | Dynactin subunit 1. | 0.999 |
ACTR1B | DCTN2 | ENSBTAP00000059768 | ENSBTAP00000066387 | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (By similarity); Belongs to the actin family. ARP1 subfamily. | Dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development (By similarity). | 0.999 |
ACTR1B | DCTN4 | ENSBTAP00000059768 | ENSBTAP00000020755 | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (By similarity); Belongs to the actin family. ARP1 subfamily. | Dynactin subunit 4. | 0.998 |
ACTR1B | DCTN6 | ENSBTAP00000059768 | ENSBTAP00000000989 | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (By similarity); Belongs to the actin family. ARP1 subfamily. | Dynactin subunit 6. | 0.998 |
CAPZA1 | ACTR1A | ENSBTAP00000056906 | ENSBTAP00000028053 | F-actin-capping protein subunit alpha-1; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions. | Actin related protein 1A. | 0.982 |
CAPZA1 | ACTR1B | ENSBTAP00000056906 | ENSBTAP00000059768 | F-actin-capping protein subunit alpha-1; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions. | Beta-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (By similarity); Belongs to the actin family. ARP1 subfamily. | 0.988 |