node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKLE2 | BANF1 | ENSBTAP00000057260 | ENSBTAP00000067190 | Ankyrin repeat and LEM domain containing 2. | Barrier-to-autointegration factor, N-terminally processed; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging. Belongs to the BAF family. | 0.836 |
ANKLE2 | EMD | ENSBTAP00000057260 | ENSBTAP00000030177 | Ankyrin repeat and LEM domain containing 2. | EMD protein. | 0.787 |
ANKLE2 | LMNA | ENSBTAP00000057260 | ENSBTAP00000023373 | Ankyrin repeat and LEM domain containing 2. | Lamin A/C; Belongs to the intermediate filament family. | 0.626 |
ANKLE2 | LMNB1 | ENSBTAP00000057260 | ENSBTAP00000069937 | Ankyrin repeat and LEM domain containing 2. | LMNB1 protein; Belongs to the intermediate filament family. | 0.545 |
ANKLE2 | RBM39 | ENSBTAP00000057260 | ENSBTAP00000060007 | Ankyrin repeat and LEM domain containing 2. | RNA binding motif protein 39. | 0.509 |
ANKLE2 | VRK1 | ENSBTAP00000057260 | ENSBTAP00000066956 | Ankyrin repeat and LEM domain containing 2. | Serine/threonine-protein kinase VRK1; Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain- containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosph [...] | 0.865 |
ANKLE2 | VRK2 | ENSBTAP00000057260 | ENSBTAP00000062023 | Ankyrin repeat and LEM domain containing 2. | VRK serine/threonine kinase 2. | 0.810 |
BANF1 | ANKLE2 | ENSBTAP00000067190 | ENSBTAP00000057260 | Barrier-to-autointegration factor, N-terminally processed; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging. Belongs to the BAF family. | Ankyrin repeat and LEM domain containing 2. | 0.836 |
BANF1 | EMD | ENSBTAP00000067190 | ENSBTAP00000030177 | Barrier-to-autointegration factor, N-terminally processed; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging. Belongs to the BAF family. | EMD protein. | 0.999 |
BANF1 | LMNA | ENSBTAP00000067190 | ENSBTAP00000023373 | Barrier-to-autointegration factor, N-terminally processed; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging. Belongs to the BAF family. | Lamin A/C; Belongs to the intermediate filament family. | 0.980 |
BANF1 | LMNB1 | ENSBTAP00000067190 | ENSBTAP00000069937 | Barrier-to-autointegration factor, N-terminally processed; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging. Belongs to the BAF family. | LMNB1 protein; Belongs to the intermediate filament family. | 0.957 |
BANF1 | LMNB2 | ENSBTAP00000067190 | ENSBTAP00000018110 | Barrier-to-autointegration factor, N-terminally processed; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging. Belongs to the BAF family. | Lamin B2; Belongs to the intermediate filament family. | 0.876 |
BANF1 | RBM39 | ENSBTAP00000067190 | ENSBTAP00000060007 | Barrier-to-autointegration factor, N-terminally processed; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging. Belongs to the BAF family. | RNA binding motif protein 39. | 0.818 |
BANF1 | SMARCA4 | ENSBTAP00000067190 | ENSBTAP00000059124 | Barrier-to-autointegration factor, N-terminally processed; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging. Belongs to the BAF family. | Transcription activator BRG1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating the calcium- dependent release of a repressor complex and the recruitment of an activator complex. In resting ne [...] | 0.903 |
BANF1 | SMARCD1 | ENSBTAP00000067190 | ENSBTAP00000001284 | Barrier-to-autointegration factor, N-terminally processed; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging. Belongs to the BAF family. | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (By similarity). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (n [...] | 0.813 |
BANF1 | VRK1 | ENSBTAP00000067190 | ENSBTAP00000066956 | Barrier-to-autointegration factor, N-terminally processed; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging. Belongs to the BAF family. | Serine/threonine-protein kinase VRK1; Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain- containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosph [...] | 0.928 |
BANF1 | VRK2 | ENSBTAP00000067190 | ENSBTAP00000062023 | Barrier-to-autointegration factor, N-terminally processed; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging. Belongs to the BAF family. | VRK serine/threonine kinase 2. | 0.868 |
EMD | ANKLE2 | ENSBTAP00000030177 | ENSBTAP00000057260 | EMD protein. | Ankyrin repeat and LEM domain containing 2. | 0.787 |
EMD | BANF1 | ENSBTAP00000030177 | ENSBTAP00000067190 | EMD protein. | Barrier-to-autointegration factor, N-terminally processed; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging. Belongs to the BAF family. | 0.999 |
EMD | LMNA | ENSBTAP00000030177 | ENSBTAP00000023373 | EMD protein. | Lamin A/C; Belongs to the intermediate filament family. | 0.999 |