STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NELL2Protein kinase C-binding protein NELL2. (816 aa)    
Predicted Functional Partners:
ROBO3
Roundabout guidance receptor 3.
    
 
 0.946
TMEM117
Transmembrane protein 117.
      
 0.634
FBXO47
F-box protein 47.
      
 0.621
MPP7
MAGUK p55 subfamily member 7; Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact (By similarity).
    
 
 0.616
CPPED1
Serine/threonine-protein phosphatase CPPED1; Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes (By similarity); Belongs to the metallophosphoesterase superfamily. CPPED1 family.
    
 
 0.549
ZNF319
Zinc finger protein 319.
    
 
 0.513
ROBO2-2
Ig-like domain-containing protein.
   
  
 0.512
ROBO2
Roundabout guidance receptor 2.
   
  
 0.512
ROBO1
Roundabout guidance receptor 1.
   
  
 0.493
SDK2
Sidekick cell adhesion molecule 2.
    
 
 0.485
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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