STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC63Coiled-coil domain-containing protein 63; Plays a role in spermiogenesis. Involved in the elongation of flagella and the formation of sperm heads. (558 aa)    
Predicted Functional Partners:
ARMC4
Armadillo repeat containing 4.
   
 
 0.888
TEKT3
Tektin-3; May be a structural component of the sperm flagellum. Required for normal sperm mobility (By similarity).
   
 
 0.779
RIBC2
RIB43A-like with coiled-coils protein 2; Belongs to the RIB43A family.
   
 
 0.776
CFAP36
Cilia- and flagella-associated protein 36; May act as an effector for ARL3.
      
 0.752
DRC7
Dynein regulatory complex subunit 7; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Involved in the regulation of flagellar motility.
   
  
 0.747
DNAH7
Dynein axonemal heavy chain 7.
   
 
 0.727
TTC29
Tetratricopeptide repeat domain 29.
   
  
 0.696
SPAG1
Sperm associated antigen 1.
    
 
 0.688
CCDC61
Coiled-coil domain containing 61.
      
 0.678
FAM216A
Protein FAM216A; Belongs to the FAM216 family.
      
 0.676
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.