| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSBTAP00000070171 | RPL11 | ENSBTAP00000070171 | ENSBTAP00000027850 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.996 |
| ENSBTAP00000070171 | RPL23 | ENSBTAP00000070171 | ENSBTAP00000004190 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | 0.996 |
| ENSBTAP00000070171 | RPS9 | ENSBTAP00000070171 | ENSBTAP00000008502 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 40S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. | 0.997 |
| ENSBTAP00000070171 | SIL1 | ENSBTAP00000070171 | ENSBTAP00000045075 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | Nucleotide exchange factor SIL1; Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5 (By similarity); Belongs to the SIL1 family. | 0.906 |
| ENSBTAP00000070171 | TUFM | ENSBTAP00000070171 | ENSBTAP00000025586 | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | Elongation factor Tu, mitochondrial; Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG- I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy. | 0.514 |
| HSPA5 | HYOU1 | ENSBTAP00000052422 | ENSBTAP00000074586 | Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...] | Hypoxia up-regulated 1. | 0.997 |
| HSPA5 | RPL11 | ENSBTAP00000052422 | ENSBTAP00000027850 | Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...] | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.432 |
| HSPA5 | RPS9 | ENSBTAP00000052422 | ENSBTAP00000008502 | Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...] | 40S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. | 0.476 |
| HSPA5 | SIL1 | ENSBTAP00000052422 | ENSBTAP00000045075 | Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...] | Nucleotide exchange factor SIL1; Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5 (By similarity); Belongs to the SIL1 family. | 0.960 |
| HYOU1 | HSPA5 | ENSBTAP00000074586 | ENSBTAP00000052422 | Hypoxia up-regulated 1. | Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...] | 0.997 |
| HYOU1 | SIL1 | ENSBTAP00000074586 | ENSBTAP00000045075 | Hypoxia up-regulated 1. | Nucleotide exchange factor SIL1; Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5 (By similarity); Belongs to the SIL1 family. | 0.960 |
| MRPL12 | MRPL36 | ENSBTAP00000048266 | ENSBTAP00000072180 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | Ribosomal protein; Belongs to the bacterial ribosomal protein bL36 family. | 0.999 |
| MRPL12 | MRPS9 | ENSBTAP00000048266 | ENSBTAP00000066078 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 28S ribosomal protein S9, mitochondrial. | 0.999 |
| MRPL12 | RPL11 | ENSBTAP00000048266 | ENSBTAP00000027850 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.998 |
| MRPL12 | RPL23 | ENSBTAP00000048266 | ENSBTAP00000004190 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | 0.999 |
| MRPL12 | RPS9 | ENSBTAP00000048266 | ENSBTAP00000008502 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 40S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. | 0.997 |
| MRPL12 | SIL1 | ENSBTAP00000048266 | ENSBTAP00000045075 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | Nucleotide exchange factor SIL1; Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5 (By similarity); Belongs to the SIL1 family. | 0.896 |
| MRPL12 | TUFM | ENSBTAP00000048266 | ENSBTAP00000025586 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | Elongation factor Tu, mitochondrial; Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG- I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy. | 0.990 |
| MRPL36 | MRPL12 | ENSBTAP00000072180 | ENSBTAP00000048266 | Ribosomal protein; Belongs to the bacterial ribosomal protein bL36 family. | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 0.999 |
| MRPL36 | MRPS9 | ENSBTAP00000072180 | ENSBTAP00000066078 | Ribosomal protein; Belongs to the bacterial ribosomal protein bL36 family. | 28S ribosomal protein S9, mitochondrial. | 0.988 |
STRING v12.5 is now available!
