node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCB6 | ALAS2 | ENSBTAP00000027459 | ENSBTAP00000067103 | ATP binding cassette subfamily B member 6. | 5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.469 |
ABCB6 | CPOX | ENSBTAP00000027459 | ENSBTAP00000005398 | ATP binding cassette subfamily B member 6. | Coproporphyrinogen oxidase. | 0.716 |
ABCB6 | FECH | ENSBTAP00000027459 | ENSBTAP00000008384 | ATP binding cassette subfamily B member 6. | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.809 |
ABCB6 | GLRX5 | ENSBTAP00000027459 | ENSBTAP00000017860 | ATP binding cassette subfamily B member 6. | Glutaredoxin 5. | 0.417 |
ABCB6 | PPOX | ENSBTAP00000027459 | ENSBTAP00000053328 | ATP binding cassette subfamily B member 6. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.754 |
ABCB6 | SLC25A38 | ENSBTAP00000027459 | ENSBTAP00000020606 | ATP binding cassette subfamily B member 6. | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. | 0.724 |
ABCB6 | UROD | ENSBTAP00000027459 | ENSBTAP00000059516 | ATP binding cassette subfamily B member 6. | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | 0.746 |
ABCB6 | UROS | ENSBTAP00000027459 | ENSBTAP00000007615 | ATP binding cassette subfamily B member 6. | Uroporphyrinogen III synthase. | 0.684 |
ABCB7 | ALAS2 | ENSBTAP00000074140 | ENSBTAP00000067103 | ATP binding cassette subfamily B member 7. | 5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.709 |
ABCB7 | CPOX | ENSBTAP00000074140 | ENSBTAP00000005398 | ATP binding cassette subfamily B member 7. | Coproporphyrinogen oxidase. | 0.550 |
ABCB7 | FECH | ENSBTAP00000074140 | ENSBTAP00000008384 | ATP binding cassette subfamily B member 7. | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.848 |
ABCB7 | GLRX5 | ENSBTAP00000074140 | ENSBTAP00000017860 | ATP binding cassette subfamily B member 7. | Glutaredoxin 5. | 0.785 |
ABCB7 | PPOX | ENSBTAP00000074140 | ENSBTAP00000053328 | ATP binding cassette subfamily B member 7. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.519 |
ABCB7 | SLC25A38 | ENSBTAP00000074140 | ENSBTAP00000020606 | ATP binding cassette subfamily B member 7. | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. | 0.752 |
ABCB7 | UROD | ENSBTAP00000074140 | ENSBTAP00000059516 | ATP binding cassette subfamily B member 7. | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | 0.496 |
ABCB7 | UROS | ENSBTAP00000074140 | ENSBTAP00000007615 | ATP binding cassette subfamily B member 7. | Uroporphyrinogen III synthase. | 0.481 |
ALAS2 | ABCB6 | ENSBTAP00000067103 | ENSBTAP00000027459 | 5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | ATP binding cassette subfamily B member 6. | 0.469 |
ALAS2 | ABCB7 | ENSBTAP00000067103 | ENSBTAP00000074140 | 5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | ATP binding cassette subfamily B member 7. | 0.709 |
ALAS2 | CPOX | ENSBTAP00000067103 | ENSBTAP00000005398 | 5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Coproporphyrinogen oxidase. | 0.780 |
ALAS2 | FECH | ENSBTAP00000067103 | ENSBTAP00000008384 | 5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.866 |