node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AP1G1 | AP1G2 | ENSBTAP00000066662 | ENSBTAP00000050701 | AP-1 complex subunit gamma. | AP-1 complex subunit gamma. | 0.904 |
AP1G1 | AP2A1 | ENSBTAP00000066662 | ENSBTAP00000061174 | AP-1 complex subunit gamma. | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | 0.641 |
AP1G1 | AP3B1 | ENSBTAP00000066662 | ENSBTAP00000006605 | AP-1 complex subunit gamma. | AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into [...] | 0.819 |
AP1G1 | AP3B2 | ENSBTAP00000066662 | ENSBTAP00000053236 | AP-1 complex subunit gamma. | AP-3 complex subunit beta. | 0.756 |
AP1G1 | AP3D1 | ENSBTAP00000066662 | ENSBTAP00000071754 | AP-1 complex subunit gamma. | AP-3 complex subunit delta-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T- cell and NK cell degranulation. In concert with the BLOC-1 complex, AP- 3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. Belongs to the adaptor complexes large subunit [...] | 0.637 |
AP1G1 | AP3M1 | ENSBTAP00000066662 | ENSBTAP00000029169 | AP-1 complex subunit gamma. | AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity). | 0.900 |
AP1G1 | AP3M2 | ENSBTAP00000066662 | ENSBTAP00000001640 | AP-1 complex subunit gamma. | AP-3 complex subunit mu-2. | 0.731 |
AP1G1 | AP4E1 | ENSBTAP00000066662 | ENSBTAP00000053599 | AP-1 complex subunit gamma. | Adaptor related protein complex 4 subunit epsilon 1. | 0.578 |
AP1G1 | F1N380_BOVIN | ENSBTAP00000066662 | ENSBTAP00000045902 | AP-1 complex subunit gamma. | Clat_adaptor_s domain-containing protein. | 0.737 |
AP1G1 | GAK | ENSBTAP00000066662 | ENSBTAP00000025537 | AP-1 complex subunit gamma. | Cyclin G associated kinase. | 0.793 |
AP1G2 | AP1G1 | ENSBTAP00000050701 | ENSBTAP00000066662 | AP-1 complex subunit gamma. | AP-1 complex subunit gamma. | 0.904 |
AP1G2 | AP2A1 | ENSBTAP00000050701 | ENSBTAP00000061174 | AP-1 complex subunit gamma. | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | 0.621 |
AP1G2 | AP3B1 | ENSBTAP00000050701 | ENSBTAP00000006605 | AP-1 complex subunit gamma. | AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into [...] | 0.756 |
AP1G2 | AP3B2 | ENSBTAP00000050701 | ENSBTAP00000053236 | AP-1 complex subunit gamma. | AP-3 complex subunit beta. | 0.756 |
AP1G2 | AP3D1 | ENSBTAP00000050701 | ENSBTAP00000071754 | AP-1 complex subunit gamma. | AP-3 complex subunit delta-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T- cell and NK cell degranulation. In concert with the BLOC-1 complex, AP- 3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. Belongs to the adaptor complexes large subunit [...] | 0.637 |
AP1G2 | AP3M1 | ENSBTAP00000050701 | ENSBTAP00000029169 | AP-1 complex subunit gamma. | AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity). | 0.774 |
AP1G2 | AP3M2 | ENSBTAP00000050701 | ENSBTAP00000001640 | AP-1 complex subunit gamma. | AP-3 complex subunit mu-2. | 0.897 |
AP1G2 | AP4E1 | ENSBTAP00000050701 | ENSBTAP00000053599 | AP-1 complex subunit gamma. | Adaptor related protein complex 4 subunit epsilon 1. | 0.635 |
AP1G2 | F1N380_BOVIN | ENSBTAP00000050701 | ENSBTAP00000045902 | AP-1 complex subunit gamma. | Clat_adaptor_s domain-containing protein. | 0.664 |
AP1G2 | GAK | ENSBTAP00000050701 | ENSBTAP00000025537 | AP-1 complex subunit gamma. | Cyclin G associated kinase. | 0.622 |