| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATP12A | ATP4A | ENSBTAP00000067109 | ENSBTAP00000011569 | Sodium/potassium-transporting ATPase subunit alpha. | Sodium/potassium-transporting ATPase subunit alpha. | 0.903 |
| ATP12A | ATP4B | ENSBTAP00000067109 | ENSBTAP00000026587 | Sodium/potassium-transporting ATPase subunit alpha. | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | 0.988 |
| ATP12A | ATP6V0A2 | ENSBTAP00000067109 | ENSBTAP00000009563 | Sodium/potassium-transporting ATPase subunit alpha. | V-type proton ATPase 116 kDa subunit a isoform 2; Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH (By similarity). In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity); Belongs to the V-ATPase 116 kDa subunit family. | 0.468 |
| ATP12A | ATP6V0A4 | ENSBTAP00000067109 | ENSBTAP00000005588 | Sodium/potassium-transporting ATPase subunit alpha. | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | 0.421 |
| ATP12A | LHPP | ENSBTAP00000067109 | ENSBTAP00000047621 | Sodium/potassium-transporting ATPase subunit alpha. | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase; Phosphatase that hydrolyzes imidodiphosphate, 3- phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency; Belongs to the HAD-like hydrolase superfamily. | 0.938 |
| ATP12A | PPA1 | ENSBTAP00000067109 | ENSBTAP00000010311 | Sodium/potassium-transporting ATPase subunit alpha. | Inorganic pyrophosphatase; Belongs to the PPase family. | 0.926 |
| ATP12A | PPA2 | ENSBTAP00000067109 | ENSBTAP00000060150 | Sodium/potassium-transporting ATPase subunit alpha. | Pyrophosphatase (inorganic) 2. | 0.920 |
| ATP4A | ATP12A | ENSBTAP00000011569 | ENSBTAP00000067109 | Sodium/potassium-transporting ATPase subunit alpha. | Sodium/potassium-transporting ATPase subunit alpha. | 0.903 |
| ATP4A | ATP4B | ENSBTAP00000011569 | ENSBTAP00000026587 | Sodium/potassium-transporting ATPase subunit alpha. | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | 0.999 |
| ATP4A | ATP6V0A2 | ENSBTAP00000011569 | ENSBTAP00000009563 | Sodium/potassium-transporting ATPase subunit alpha. | V-type proton ATPase 116 kDa subunit a isoform 2; Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH (By similarity). In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity); Belongs to the V-ATPase 116 kDa subunit family. | 0.564 |
| ATP4A | ATP6V0A4 | ENSBTAP00000011569 | ENSBTAP00000005588 | Sodium/potassium-transporting ATPase subunit alpha. | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | 0.534 |
| ATP4A | LHPP | ENSBTAP00000011569 | ENSBTAP00000047621 | Sodium/potassium-transporting ATPase subunit alpha. | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase; Phosphatase that hydrolyzes imidodiphosphate, 3- phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency; Belongs to the HAD-like hydrolase superfamily. | 0.935 |
| ATP4A | PPA1 | ENSBTAP00000011569 | ENSBTAP00000010311 | Sodium/potassium-transporting ATPase subunit alpha. | Inorganic pyrophosphatase; Belongs to the PPase family. | 0.923 |
| ATP4A | PPA2 | ENSBTAP00000011569 | ENSBTAP00000060150 | Sodium/potassium-transporting ATPase subunit alpha. | Pyrophosphatase (inorganic) 2. | 0.920 |
| ATP4B | ATP12A | ENSBTAP00000026587 | ENSBTAP00000067109 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | Sodium/potassium-transporting ATPase subunit alpha. | 0.988 |
| ATP4B | ATP4A | ENSBTAP00000026587 | ENSBTAP00000011569 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | Sodium/potassium-transporting ATPase subunit alpha. | 0.999 |
| ATP4B | ATP6V0A4 | ENSBTAP00000026587 | ENSBTAP00000005588 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | 0.455 |
| ATP4B | LHPP | ENSBTAP00000026587 | ENSBTAP00000047621 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase; Phosphatase that hydrolyzes imidodiphosphate, 3- phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency; Belongs to the HAD-like hydrolase superfamily. | 0.929 |
| ATP4B | PPA1 | ENSBTAP00000026587 | ENSBTAP00000010311 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | Inorganic pyrophosphatase; Belongs to the PPase family. | 0.918 |
| ATP4B | PPA2 | ENSBTAP00000026587 | ENSBTAP00000060150 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | Pyrophosphatase (inorganic) 2. | 0.919 |