STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMPOSplenin; Hormone of the spleen with pleiotropic actions on prothymocytes, mature T-cells, the nicotinic acetylcholine receptor, and pituitary corticotrophs. (457 aa)    
Predicted Functional Partners:
LMNA
Lamin A/C; Belongs to the intermediate filament family.
   
 
 0.880
LBR
Lamin B receptor.
   
 
 0.781
LMNB1
LMNB1 protein; Belongs to the intermediate filament family.
   
 
 0.760
BANF1
Barrier-to-autointegration factor, N-terminally processed; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging. Belongs to the BAF family.
    
 
 0.742
G2E3
G2/M-phase specific E3 ubiquitin protein ligase.
   
 
 0.681
GAS2L3
Growth arrest specific 2 like 3.
   
 
 0.672
KIF20B
Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.670
CCDC183
Coiled-coil domain containing 183.
    
 
 0.663
CKAP5
Cytoskeleton associated protein 5.
   
 
 0.654
DEK
DEK proto-oncogene.
   
 
 0.652
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.