node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NPBWR2 | NPY | ENSBTAP00000054391 | ENSBTAP00000061725 | Neuropeptides B/W receptor type 2; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity); Belongs to the G-protein coupled receptor 1 family. | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | 0.641 |
NPBWR2 | NPY1R | ENSBTAP00000054391 | ENSBTAP00000055219 | Neuropeptides B/W receptor type 2; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity); Belongs to the G-protein coupled receptor 1 family. | Neuropeptide Y receptor type 1; Receptor for neuropeptide Y and peptide YY; Belongs to the G-protein coupled receptor 1 family. | 0.503 |
NPBWR2 | NPY5R | ENSBTAP00000054391 | ENSBTAP00000048615 | Neuropeptides B/W receptor type 2; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity); Belongs to the G-protein coupled receptor 1 family. | Neuropeptide Y receptor Y5. | 0.687 |
NPBWR2 | POMC | ENSBTAP00000054391 | ENSBTAP00000010386 | Neuropeptides B/W receptor type 2; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity); Belongs to the G-protein coupled receptor 1 family. | Corticotropin-like intermediary peptide; [Corticotropin]: Stimulates the adrenal glands to release cortisol. [Beta-endorphin]: Endogenous orexigenic opiate. | 0.658 |
NPBWR2 | PPY | ENSBTAP00000054391 | ENSBTAP00000040571 | Neuropeptides B/W receptor type 2; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity); Belongs to the G-protein coupled receptor 1 family. | Pancreatic prohormone; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions; Belongs to the NPY family. | 0.649 |
NPBWR2 | PYY | ENSBTAP00000054391 | ENSBTAP00000055348 | Neuropeptides B/W receptor type 2; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity); Belongs to the G-protein coupled receptor 1 family. | Peptide YY; This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility; Belongs to the NPY family. | 0.518 |
NPBWR2 | SST | ENSBTAP00000054391 | ENSBTAP00000023020 | Neuropeptides B/W receptor type 2; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity); Belongs to the G-protein coupled receptor 1 family. | Somatostatin-14; [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin. | 0.652 |
NPBWR2 | SSTR1 | ENSBTAP00000054391 | ENSBTAP00000008645 | Neuropeptides B/W receptor type 2; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity); Belongs to the G-protein coupled receptor 1 family. | Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family. | 0.522 |
NPBWR2 | SSTR3 | ENSBTAP00000054391 | ENSBTAP00000053989 | Neuropeptides B/W receptor type 2; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity); Belongs to the G-protein coupled receptor 1 family. | Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. | 0.539 |
NPY | NPBWR2 | ENSBTAP00000061725 | ENSBTAP00000054391 | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | Neuropeptides B/W receptor type 2; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity); Belongs to the G-protein coupled receptor 1 family. | 0.641 |
NPY | NPY1R | ENSBTAP00000061725 | ENSBTAP00000055219 | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | Neuropeptide Y receptor type 1; Receptor for neuropeptide Y and peptide YY; Belongs to the G-protein coupled receptor 1 family. | 0.985 |
NPY | NPY5R | ENSBTAP00000061725 | ENSBTAP00000048615 | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | Neuropeptide Y receptor Y5. | 0.952 |
NPY | POMC | ENSBTAP00000061725 | ENSBTAP00000010386 | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | Corticotropin-like intermediary peptide; [Corticotropin]: Stimulates the adrenal glands to release cortisol. [Beta-endorphin]: Endogenous orexigenic opiate. | 0.989 |
NPY | PPY | ENSBTAP00000061725 | ENSBTAP00000040571 | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | Pancreatic prohormone; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions; Belongs to the NPY family. | 0.942 |
NPY | PYY | ENSBTAP00000061725 | ENSBTAP00000055348 | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | Peptide YY; This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility; Belongs to the NPY family. | 0.911 |
NPY | PYY2 | ENSBTAP00000061725 | ENSBTAP00000054402 | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | Caltrin; Inhibits calcium transport into spermatozoa; it does not bind directly to calcium. Binds to calmodulin. Inhibits the growth of microorganisms. Seem to act as an antibiotic by permeabilizing the bacterial membrane. | 0.985 |
NPY | SST | ENSBTAP00000061725 | ENSBTAP00000023020 | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | Somatostatin-14; [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin. | 0.948 |
NPY | SSTR1 | ENSBTAP00000061725 | ENSBTAP00000008645 | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family. | 0.739 |
NPY | SSTR3 | ENSBTAP00000061725 | ENSBTAP00000053989 | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. | 0.632 |
NPY1R | NPBWR2 | ENSBTAP00000055219 | ENSBTAP00000054391 | Neuropeptide Y receptor type 1; Receptor for neuropeptide Y and peptide YY; Belongs to the G-protein coupled receptor 1 family. | Neuropeptides B/W receptor type 2; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity); Belongs to the G-protein coupled receptor 1 family. | 0.503 |