node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACR | PRM2 | ENSBTAP00000013434 | ENSBTAP00000062174 | Acrosin; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome. | Protamine-2; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. | 0.611 |
ACR | SYCP3 | ENSBTAP00000013434 | ENSBTAP00000071106 | Acrosin; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome. | Synaptonemal complex protein 3; Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells. Required for normal meiosis during spermatogenesis and male fertility. Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2. | 0.688 |
ACR | TNP1 | ENSBTAP00000013434 | ENSBTAP00000025292 | Acrosin; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome. | Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.855 |
ACR | TNP2 | ENSBTAP00000013434 | ENSBTAP00000048966 | Acrosin; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome. | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. Belongs to the nuclear transition protein 2 family. | 0.645 |
FAM170A | SPEM1 | ENSBTAP00000003964 | ENSBTAP00000042433 | Family with sequence similarity 170 member A. | Spermatid maturation protein 1; Required for proper cytoplasm removal during spermatogenesis. | 0.766 |
FAM170A | TNP1 | ENSBTAP00000003964 | ENSBTAP00000025292 | Family with sequence similarity 170 member A. | Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.703 |
FAM170A | TNP2 | ENSBTAP00000003964 | ENSBTAP00000048966 | Family with sequence similarity 170 member A. | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. Belongs to the nuclear transition protein 2 family. | 0.638 |
IQCF1 | PRM2 | ENSBTAP00000001065 | ENSBTAP00000062174 | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | Protamine-2; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. | 0.584 |
IQCF1 | SPEM1 | ENSBTAP00000001065 | ENSBTAP00000042433 | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | Spermatid maturation protein 1; Required for proper cytoplasm removal during spermatogenesis. | 0.582 |
IQCF1 | TNP1 | ENSBTAP00000001065 | ENSBTAP00000025292 | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.623 |
IQCF1 | TNP2 | ENSBTAP00000001065 | ENSBTAP00000048966 | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. Belongs to the nuclear transition protein 2 family. | 0.702 |
LOC404073 | PRM1 | ENSBTAP00000016978 | ENSBTAP00000043964 | Histone H2B subacrosomal variant; May act as an acrosome-nuclear docking protein in sperm. | Sperm protamine P1. | 0.747 |
LOC404073 | TNP1 | ENSBTAP00000016978 | ENSBTAP00000025292 | Histone H2B subacrosomal variant; May act as an acrosome-nuclear docking protein in sperm. | Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.680 |
LOC404073 | TNP2 | ENSBTAP00000016978 | ENSBTAP00000048966 | Histone H2B subacrosomal variant; May act as an acrosome-nuclear docking protein in sperm. | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. Belongs to the nuclear transition protein 2 family. | 0.814 |
PRM1 | LOC404073 | ENSBTAP00000043964 | ENSBTAP00000016978 | Sperm protamine P1. | Histone H2B subacrosomal variant; May act as an acrosome-nuclear docking protein in sperm. | 0.747 |
PRM1 | PRM2 | ENSBTAP00000043964 | ENSBTAP00000062174 | Sperm protamine P1. | Protamine-2; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. | 0.710 |
PRM1 | TNP1 | ENSBTAP00000043964 | ENSBTAP00000025292 | Sperm protamine P1. | Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.967 |
PRM1 | TNP2 | ENSBTAP00000043964 | ENSBTAP00000048966 | Sperm protamine P1. | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. Belongs to the nuclear transition protein 2 family. | 0.864 |
PRM2 | ACR | ENSBTAP00000062174 | ENSBTAP00000013434 | Protamine-2; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. | Acrosin; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome. | 0.611 |
PRM2 | IQCF1 | ENSBTAP00000062174 | ENSBTAP00000001065 | Protamine-2; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | 0.584 |