| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGTPBP1 | OXR1 | ENSBTAP00000064975 | ENSBTAP00000069923 | ATP/GTP binding protein 1. | Oxidation resistance protein 1; May be involved in protection from oxidative damage. Belongs to the OXR1 family. | 0.581 |
| ATP6V1B1 | OXR1 | ENSBTAP00000014039 | ENSBTAP00000069923 | V-type proton ATPase subunit B, kidney isoform; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | Oxidation resistance protein 1; May be involved in protection from oxidative damage. Belongs to the OXR1 family. | 0.655 |
| ATP6V1B1 | TMEM150A | ENSBTAP00000014039 | ENSBTAP00000024342 | V-type proton ATPase subunit B, kidney isoform; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | Transmembrane protein 150A. | 0.407 |
| CDC16 | OXR1 | ENSBTAP00000026604 | ENSBTAP00000069923 | Cell division cycle 16. | Oxidation resistance protein 1; May be involved in protection from oxidative damage. Belongs to the OXR1 family. | 0.567 |
| FRMD4A | HSPH1 | ENSBTAP00000010894 | ENSBTAP00000006600 | FERM domain containing 4A. | Heat shock protein 105 kDa; Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering substrate release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. | 0.692 |
| FRMD4A | OXR1 | ENSBTAP00000010894 | ENSBTAP00000069923 | FERM domain containing 4A. | Oxidation resistance protein 1; May be involved in protection from oxidative damage. Belongs to the OXR1 family. | 0.569 |
| FRMD4A | RPS6KA6 | ENSBTAP00000010894 | ENSBTAP00000062237 | FERM domain containing 4A. | Ribosomal protein S6 kinase. | 0.631 |
| FRMD4A | SH3BGRL | ENSBTAP00000010894 | ENSBTAP00000013990 | FERM domain containing 4A. | SH3 domain-binding glutamic acid-rich-like protein; Belongs to the SH3BGR family. | 0.635 |
| FRMD4A | TMEM150A | ENSBTAP00000010894 | ENSBTAP00000024342 | FERM domain containing 4A. | Transmembrane protein 150A. | 0.773 |
| HCRT | HCRTR1 | ENSBTAP00000000875 | ENSBTAP00000062326 | Orexin-A; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity (By similarity). | Orexin receptor type 1; Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding. | 0.977 |
| HCRT | OXR1 | ENSBTAP00000000875 | ENSBTAP00000069923 | Orexin-A; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity (By similarity). | Oxidation resistance protein 1; May be involved in protection from oxidative damage. Belongs to the OXR1 family. | 0.755 |
| HCRTR1 | HCRT | ENSBTAP00000062326 | ENSBTAP00000000875 | Orexin receptor type 1; Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding. | Orexin-A; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity (By similarity). | 0.977 |
| HCRTR1 | OXR1 | ENSBTAP00000062326 | ENSBTAP00000069923 | Orexin receptor type 1; Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding. | Oxidation resistance protein 1; May be involved in protection from oxidative damage. Belongs to the OXR1 family. | 0.679 |
| HSPH1 | FRMD4A | ENSBTAP00000006600 | ENSBTAP00000010894 | Heat shock protein 105 kDa; Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering substrate release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. | FERM domain containing 4A. | 0.692 |
| HSPH1 | OXR1 | ENSBTAP00000006600 | ENSBTAP00000069923 | Heat shock protein 105 kDa; Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering substrate release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. | Oxidation resistance protein 1; May be involved in protection from oxidative damage. Belongs to the OXR1 family. | 0.572 |
| HSPH1 | RPS6KA6 | ENSBTAP00000006600 | ENSBTAP00000062237 | Heat shock protein 105 kDa; Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering substrate release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. | Ribosomal protein S6 kinase. | 0.669 |
| HSPH1 | SH3BGRL | ENSBTAP00000006600 | ENSBTAP00000013990 | Heat shock protein 105 kDa; Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering substrate release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. | SH3 domain-binding glutamic acid-rich-like protein; Belongs to the SH3BGR family. | 0.694 |
| HSPH1 | TMEM150A | ENSBTAP00000006600 | ENSBTAP00000024342 | Heat shock protein 105 kDa; Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering substrate release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. | Transmembrane protein 150A. | 0.771 |
| OXR1 | AGTPBP1 | ENSBTAP00000069923 | ENSBTAP00000064975 | Oxidation resistance protein 1; May be involved in protection from oxidative damage. Belongs to the OXR1 family. | ATP/GTP binding protein 1. | 0.581 |
| OXR1 | ATP6V1B1 | ENSBTAP00000069923 | ENSBTAP00000014039 | Oxidation resistance protein 1; May be involved in protection from oxidative damage. Belongs to the OXR1 family. | V-type proton ATPase subunit B, kidney isoform; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.655 |
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