node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENPP1 | ENPP3 | ENSBTAP00000053402 | ENSBTAP00000026900 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic [...] | 0.905 |
ENPP1 | GUCY1A1 | ENSBTAP00000053402 | ENSBTAP00000064987 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Guanylate cyclase soluble subunit alpha-1. | 0.902 |
ENPP1 | GUCY1A2 | ENSBTAP00000053402 | ENSBTAP00000053417 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.902 |
ENPP1 | GUCY1B1 | ENSBTAP00000053402 | ENSBTAP00000005009 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Guanylate cyclase soluble subunit beta-1; Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.907 |
ENPP1 | ITPA | ENSBTAP00000053402 | ENSBTAP00000072806 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.908 |
ENPP1 | PKLR | ENSBTAP00000053402 | ENSBTAP00000061000 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.901 |
ENPP1 | PKM | ENSBTAP00000053402 | ENSBTAP00000044619 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.901 |
ENPP3 | ENPP1 | ENSBTAP00000026900 | ENSBTAP00000053402 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic [...] | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.905 |
ENPP3 | GUCY1A1 | ENSBTAP00000026900 | ENSBTAP00000064987 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic [...] | Guanylate cyclase soluble subunit alpha-1. | 0.902 |
ENPP3 | GUCY1A2 | ENSBTAP00000026900 | ENSBTAP00000053417 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic [...] | Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.902 |
ENPP3 | GUCY1B1 | ENSBTAP00000026900 | ENSBTAP00000005009 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic [...] | Guanylate cyclase soluble subunit beta-1; Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.907 |
ENPP3 | ITPA | ENSBTAP00000026900 | ENSBTAP00000072806 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic [...] | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.925 |
ENPP3 | PKLR | ENSBTAP00000026900 | ENSBTAP00000061000 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic [...] | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.901 |
ENPP3 | PKM | ENSBTAP00000026900 | ENSBTAP00000044619 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic [...] | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.901 |
GUCY1A1 | ENPP1 | ENSBTAP00000064987 | ENSBTAP00000053402 | Guanylate cyclase soluble subunit alpha-1. | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.902 |
GUCY1A1 | ENPP3 | ENSBTAP00000064987 | ENSBTAP00000026900 | Guanylate cyclase soluble subunit alpha-1. | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic [...] | 0.902 |
GUCY1A1 | GUCY1A2 | ENSBTAP00000064987 | ENSBTAP00000053417 | Guanylate cyclase soluble subunit alpha-1. | Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.839 |
GUCY1A1 | GUCY1B1 | ENSBTAP00000064987 | ENSBTAP00000005009 | Guanylate cyclase soluble subunit alpha-1. | Guanylate cyclase soluble subunit beta-1; Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.996 |
GUCY1A1 | ITPA | ENSBTAP00000064987 | ENSBTAP00000072806 | Guanylate cyclase soluble subunit alpha-1. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.913 |
GUCY1A1 | NOS1 | ENSBTAP00000064987 | ENSBTAP00000065649 | Guanylate cyclase soluble subunit alpha-1. | Nitric oxide synthase; Produces nitric oxide (NO). | 0.907 |