STRINGSTRING
AVPR2 protein (Bos taurus) - STRING interaction network
"AVPR2" - Vasopressin V2 receptor in Bos taurus
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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AVPR2Vasopressin V2 receptor ; Receptor for arginine vasopressin (PubMed-7698346, PubMed-8257689). The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption (By similarity) (370 aa)    
Predicted Functional Partners:
ARRB1
Beta-arrestin-1 ; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G- protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin-associated sorting proteins) and re [...] (418 aa)
     
  0.974
AVP
Vasopressin-neurophysin 2-copeptin Arg-vasopressin Neurophysin 2 Copeptin; Neurophysin 2 specifically binds vasopressin (166 aa)
     
  0.954
ADRB2
Beta-2 adrenergic receptor ; Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity) (418 aa)
         
  0.941
DRD1
D(1A) dopamine receptor ; Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase (446 aa)
     
 
  0.937
SH3GL2
endophilin-A1 (352 aa)
     
  0.931
GNG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 ; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (71 aa)
       
  0.928
GNB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 ; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (340 aa)
       
    0.925
GNB3
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 (340 aa)
       
    0.925
GNB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 ; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (340 aa)
       
    0.925
GNB4
Guanine nucleotide-binding protein subunit beta-4 (340 aa)
       
    0.925
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae, Bovidae sp. Adi Nefas, Bovinae, Pecora, Ruminantia, bovine, cattle, cow, domestic cattle, domestic cow, oxen, cattle
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