node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADGRL1 | LRRC4 | ENSBTAP00000073270 | ENSBTAP00000056438 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity). | Leucine rich repeat containing 4 protein. | 0.678 |
ADGRL1 | LRRC43 | ENSBTAP00000073270 | ENSBTAP00000055995 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity). | Leucine rich repeat containing 43. | 0.611 |
ADGRL2 | LRRC4 | ENSBTAP00000055886 | ENSBTAP00000056438 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Leucine rich repeat containing 4 protein. | 0.678 |
ADGRL2 | LRRC43 | ENSBTAP00000055886 | ENSBTAP00000055995 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Leucine rich repeat containing 43. | 0.611 |
ADGRL3 | LRRC4 | ENSBTAP00000049222 | ENSBTAP00000056438 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | Leucine rich repeat containing 4 protein. | 0.678 |
ADGRL3 | LRRC43 | ENSBTAP00000049222 | ENSBTAP00000055995 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | Leucine rich repeat containing 43. | 0.611 |
LRRC4 | ADGRL1 | ENSBTAP00000056438 | ENSBTAP00000073270 | Leucine rich repeat containing 4 protein. | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity). | 0.678 |
LRRC4 | ADGRL2 | ENSBTAP00000056438 | ENSBTAP00000055886 | Leucine rich repeat containing 4 protein. | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | 0.678 |
LRRC4 | ADGRL3 | ENSBTAP00000056438 | ENSBTAP00000049222 | Leucine rich repeat containing 4 protein. | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | 0.678 |
LRRC4 | LRRC43 | ENSBTAP00000056438 | ENSBTAP00000055995 | Leucine rich repeat containing 4 protein. | Leucine rich repeat containing 43. | 0.763 |
LRRC43 | ADGRL1 | ENSBTAP00000055995 | ENSBTAP00000073270 | Leucine rich repeat containing 43. | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity). | 0.611 |
LRRC43 | ADGRL2 | ENSBTAP00000055995 | ENSBTAP00000055886 | Leucine rich repeat containing 43. | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | 0.611 |
LRRC43 | ADGRL3 | ENSBTAP00000055995 | ENSBTAP00000049222 | Leucine rich repeat containing 43. | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | 0.611 |
LRRC43 | LRRC4 | ENSBTAP00000055995 | ENSBTAP00000056438 | Leucine rich repeat containing 43. | Leucine rich repeat containing 4 protein. | 0.763 |
LRRC43 | PPP1CA | ENSBTAP00000055995 | ENSBTAP00000016111 | Leucine rich repeat containing 43. | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin de [...] | 0.594 |
LRRC43 | PPP1CC | ENSBTAP00000055995 | ENSBTAP00000072697 | Leucine rich repeat containing 43. | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density- asso [...] | 0.594 |
LRRC43 | PPP1R3A | ENSBTAP00000055995 | ENSBTAP00000008851 | Leucine rich repeat containing 43. | Protein phosphatase 1 regulatory subunit 3A. | 0.564 |
LRRC43 | PPP1R3B | ENSBTAP00000055995 | ENSBTAP00000014032 | Leucine rich repeat containing 43. | Protein phosphatase 1 regulatory subunit 3B; Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated gl [...] | 0.564 |
LRRC43 | PPP1R3C | ENSBTAP00000055995 | ENSBTAP00000019753 | Leucine rich repeat containing 43. | Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types (By similarity). | 0.564 |
LRRC43 | UBXN10 | ENSBTAP00000055995 | ENSBTAP00000052187 | Leucine rich repeat containing 43. | UBX domain protein 10. | 0.797 |