node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCAR4 | SLBP2 | ENSBTAP00000056316 | ENSBTAP00000056021 | Breast cancer anti-estrogen resistance 4 transcript variant 1. | Stem loop binding protein 2 short isoform. | 0.662 |
CTIF | MIF4GD | ENSBTAP00000066839 | ENSBTAP00000034575 | Cap binding complex dependent translation initiation factor. | MIF4G domain-containing protein; Functions in replication-dependent translation of histone mRNAs which differ from other eukaryotic mRNAs in that they do not end with a poly-A tail but a stem-loop. May participate in circularizing those mRNAs specifically enhancing their translation (By similarity). | 0.682 |
CTIF | SLBP | ENSBTAP00000066839 | ENSBTAP00000062520 | Cap binding complex dependent translation initiation factor. | Stem-loop binding protein. | 0.866 |
CTIF | SLBP2 | ENSBTAP00000066839 | ENSBTAP00000056021 | Cap binding complex dependent translation initiation factor. | Stem loop binding protein 2 short isoform. | 0.659 |
ENSBTAP00000060463 | SLBP | ENSBTAP00000060463 | ENSBTAP00000062520 | SAP domain-containing protein. | Stem-loop binding protein. | 0.665 |
ENSBTAP00000060463 | SLBP2 | ENSBTAP00000060463 | ENSBTAP00000056021 | SAP domain-containing protein. | Stem loop binding protein 2 short isoform. | 0.665 |
ERI1 | SLBP | ENSBTAP00000012775 | ENSBTAP00000062520 | Three prime histone mRNA exonuclease 1. | Stem-loop binding protein. | 0.732 |
ERI1 | SLBP2 | ENSBTAP00000012775 | ENSBTAP00000056021 | Three prime histone mRNA exonuclease 1. | Stem loop binding protein 2 short isoform. | 0.665 |
MCM7 | PCNA | ENSBTAP00000003728 | ENSBTAP00000007967 | DNA replication licensing factor MCM7; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | 0.959 |
MCM7 | RRM1 | ENSBTAP00000003728 | ENSBTAP00000017428 | DNA replication licensing factor MCM7; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.903 |
MCM7 | RRM2 | ENSBTAP00000003728 | ENSBTAP00000010802 | DNA replication licensing factor MCM7; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Ribonucleotide reductase regulatory subunit M2. | 0.873 |
MCM7 | SLBP | ENSBTAP00000003728 | ENSBTAP00000062520 | DNA replication licensing factor MCM7; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Stem-loop binding protein. | 0.635 |
MCM7 | SLBP2 | ENSBTAP00000003728 | ENSBTAP00000056021 | DNA replication licensing factor MCM7; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Stem loop binding protein 2 short isoform. | 0.557 |
MIF4GD | CTIF | ENSBTAP00000034575 | ENSBTAP00000066839 | MIF4G domain-containing protein; Functions in replication-dependent translation of histone mRNAs which differ from other eukaryotic mRNAs in that they do not end with a poly-A tail but a stem-loop. May participate in circularizing those mRNAs specifically enhancing their translation (By similarity). | Cap binding complex dependent translation initiation factor. | 0.682 |
MIF4GD | SLBP | ENSBTAP00000034575 | ENSBTAP00000062520 | MIF4G domain-containing protein; Functions in replication-dependent translation of histone mRNAs which differ from other eukaryotic mRNAs in that they do not end with a poly-A tail but a stem-loop. May participate in circularizing those mRNAs specifically enhancing their translation (By similarity). | Stem-loop binding protein. | 0.734 |
MIF4GD | SLBP2 | ENSBTAP00000034575 | ENSBTAP00000056021 | MIF4G domain-containing protein; Functions in replication-dependent translation of histone mRNAs which differ from other eukaryotic mRNAs in that they do not end with a poly-A tail but a stem-loop. May participate in circularizing those mRNAs specifically enhancing their translation (By similarity). | Stem loop binding protein 2 short isoform. | 0.734 |
PCNA | MCM7 | ENSBTAP00000007967 | ENSBTAP00000003728 | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | DNA replication licensing factor MCM7; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.959 |
PCNA | RRM1 | ENSBTAP00000007967 | ENSBTAP00000017428 | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.908 |
PCNA | RRM2 | ENSBTAP00000007967 | ENSBTAP00000010802 | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | Ribonucleotide reductase regulatory subunit M2. | 0.818 |
PCNA | SLBP | ENSBTAP00000007967 | ENSBTAP00000062520 | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | Stem-loop binding protein. | 0.619 |