STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SETD5SET domain containing 5. (1497 aa)    
Predicted Functional Partners:
KMT2A
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
   
 
0.822
THUMPD3
THUMP domain-containing protein 3; Belongs to the methyltransferase superfamily.
      
 0.813
CHD8
Chromodomain helicase DNA binding protein 8.
   
 
 0.804
KMT2E
Lysine methyltransferase 2E.
   
0.802
SETD2
SET domain containing 2, histone lysine methyltransferase.
   
 
0.787
KMT2C
Lysine methyltransferase 2C.
   
  
0.785
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
   
 
 0.765
EP300
E1A binding protein p300.
   
 
 0.736
TNRC6A
Trinucleotide repeat containing adaptor 6A.
   
  
 0.726
ASH1L
ASH1 like histone lysine methyltransferase.
   
 
0.707
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.