STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YIPF3Yip1 domain family member 3. (348 aa)    
Predicted Functional Partners:
POLR1C
DNA-directed RNA polymerases I and III subunit RPAC1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).
      
 0.740
OCEL1
Occludin_ELL domain-containing protein.
   
  
 0.681
PHYHD1
Phytanoyl-CoA dioxygenase domain-containing protein 1; Has alpha-ketoglutarate-dependent dioxygenase activity. Does not show detectable activity towards fatty acid CoA thioesters. Is not expected to be active with phytanoyl CoA (By similarity). Belongs to the PhyH family. PHYHD1 subfamily.
   
  
 0.672
YIPF4
Protein YIPF.
   
 
 0.662
DHRS12
Dehydrogenase/reductase SDR family member 12; Putative oxidoreductase.
   
  
 0.662
TLCD1
TLC domain containing 1.
      
 0.659
CDC42EP5
CDC42 effector protein 5.
   
  
 0.593
SUMF2
Inactive C-alpha-formylglycine-generating enzyme 2; Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1. Belongs to the sulfatase-modifying factor family.
   
 
 0.589
ARMCX3
Armadillo repeat containing X-linked 3.
    
 
 0.583
IFI27L2
Interferon alpha-inducible protein 27-like protein 2; Plays a role in the apoptotic process and has a pro-apoptotic activity; Belongs to the IFI6/IFI27 family.
   
  
 0.572
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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