STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DVL2Dishevelled segment polarity protein 2. (740 aa)    
Predicted Functional Partners:
VANGL1
Vang-like protein.
    
 0.995
VANGL2
Vang-like protein.
    
 0.991
DACT1
Dishevelled binding antagonist of beta catenin 1.
    
 0.980
PRICKLE2
Prickle planar cell polarity protein 2.
    
 0.980
PRICKLE1
Prickle planar cell polarity protein 1.
    
 0.980
DAAM1
Dishevelled associated activator of morphogenesis 1.
    
 0.974
AXIN2
Axin 2.
   
0.973
GSK3B
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.973
LRP6
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.972
DVL1
Uncharacterized protein.
  
 
0.968
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.