node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARHGAP42 | ATP6V1E2 | ENSBTAP00000057783 | ENSBTAP00000018250 | Rho GTPase activating protein 42. | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | 0.817 |
ARHGAP42 | MAIP1 | ENSBTAP00000057783 | ENSBTAP00000025606 | Rho GTPase activating protein 42. | m-AAA protease-interacting protein 1, mitochondrial; Promotes sorting of SMDT1/EMRE in mitochondria by ensuring its maturation. Interacts with the transit peptide region of SMDT1/EMRE precursor protein in the mitochondrial matrix, leading to protect it against protein degradation by YME1L1, thereby ensuring SMDT1/EMRE maturation by the mitochondrial processing peptidase (PMPCA and PMPCB). | 0.807 |
ARHGAP42 | MEIOC | ENSBTAP00000057783 | ENSBTAP00000040543 | Rho GTPase activating protein 42. | Meiosis specific with coiled-coil domain. | 0.791 |
ARHGAP42 | NEPRO | ENSBTAP00000057783 | ENSBTAP00000007523 | Rho GTPase activating protein 42. | Nucleolus and neural progenitor protein. | 0.839 |
ARHGAP42 | OR1P1 | ENSBTAP00000057783 | ENSBTAP00000025838 | Rho GTPase activating protein 42. | Olfactory receptor. | 0.744 |
ARHGAP42 | OR2G2 | ENSBTAP00000057783 | ENSBTAP00000050676 | Rho GTPase activating protein 42. | Olfactory receptor. | 0.726 |
ARHGAP42 | OR2G2-2 | ENSBTAP00000057783 | ENSBTAP00000049133 | Rho GTPase activating protein 42. | Olfactory receptor. | 0.726 |
ARHGAP42 | PRSS56 | ENSBTAP00000057783 | ENSBTAP00000069940 | Rho GTPase activating protein 42. | Serine protease 56; Belongs to the peptidase S1 family. | 0.713 |
ARHGAP42 | STOX2 | ENSBTAP00000057783 | ENSBTAP00000065876 | Rho GTPase activating protein 42. | Storkhead box 2. | 0.783 |
ARHGAP42 | UVSSA | ENSBTAP00000057783 | ENSBTAP00000016697 | Rho GTPase activating protein 42. | UV-stimulated scaffold protein A; Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to [...] | 0.757 |
ATP6V1E2 | ARHGAP42 | ENSBTAP00000018250 | ENSBTAP00000057783 | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | Rho GTPase activating protein 42. | 0.817 |
ATP6V1E2 | MAIP1 | ENSBTAP00000018250 | ENSBTAP00000025606 | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | m-AAA protease-interacting protein 1, mitochondrial; Promotes sorting of SMDT1/EMRE in mitochondria by ensuring its maturation. Interacts with the transit peptide region of SMDT1/EMRE precursor protein in the mitochondrial matrix, leading to protect it against protein degradation by YME1L1, thereby ensuring SMDT1/EMRE maturation by the mitochondrial processing peptidase (PMPCA and PMPCB). | 0.795 |
ATP6V1E2 | MEIOC | ENSBTAP00000018250 | ENSBTAP00000040543 | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | Meiosis specific with coiled-coil domain. | 0.701 |
ATP6V1E2 | NEPRO | ENSBTAP00000018250 | ENSBTAP00000007523 | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | Nucleolus and neural progenitor protein. | 0.817 |
ATP6V1E2 | OR1P1 | ENSBTAP00000018250 | ENSBTAP00000025838 | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | Olfactory receptor. | 0.571 |
ATP6V1E2 | OR2G2 | ENSBTAP00000018250 | ENSBTAP00000050676 | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | Olfactory receptor. | 0.694 |
ATP6V1E2 | OR2G2-2 | ENSBTAP00000018250 | ENSBTAP00000049133 | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | Olfactory receptor. | 0.715 |
ATP6V1E2 | PRSS56 | ENSBTAP00000018250 | ENSBTAP00000069940 | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | Serine protease 56; Belongs to the peptidase S1 family. | 0.678 |
ATP6V1E2 | STOX2 | ENSBTAP00000018250 | ENSBTAP00000065876 | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | Storkhead box 2. | 0.818 |
ATP6V1E2 | UVSSA | ENSBTAP00000018250 | ENSBTAP00000016697 | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | UV-stimulated scaffold protein A; Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to [...] | 0.673 |