STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC180Coiled-coil domain containing 180. (1624 aa)    
Predicted Functional Partners:
BLOC1S5
Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).
      
 0.727
SCHIP1
SCHIP-1 domain-containing protein.
      
 0.688
ZNF345
Zinc finger protein 345; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
    
 
 0.675
FAM92A
Protein FAM92A; Acts as a positive regulator of ciliary hedgehog signaling (By similarity). Probable regulator of ciliogenesis involved in limb morphogenesis. In cooperation with CBY1 it is involved in the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis; Belongs to the FAM92 family.
      
 0.577
HHAT
Hedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family.
      
 0.576
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
   
 
 0.557
LOC507550
Uncharacterized protein.
 
      0.547
LRP1
LDL receptor related protein 1.
      
 0.542
PILRA
IG domain-containing protein.
      
 0.510
SLAMF8
SLAM family member 8.
   
  
 0.490
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.