| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACVR1 | BMP10 | ENSBTAP00000015797 | ENSBTAP00000001312 | Activin receptor type-1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May also bind activin; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Bone morphogenetic protein 10. | 0.878 |
| ACVR1 | BMP2 | ENSBTAP00000015797 | ENSBTAP00000006739 | Activin receptor type-1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May also bind activin; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Bone morphogenetic protein 2. | 0.980 |
| ACVR1 | BMP4 | ENSBTAP00000015797 | ENSBTAP00000004992 | Activin receptor type-1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May also bind activin; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). | 0.984 |
| ACVR1 | BMP7 | ENSBTAP00000015797 | ENSBTAP00000053246 | Activin receptor type-1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May also bind activin; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Bone morphogenetic protein 7. | 0.986 |
| ACVR1 | BMPR1A | ENSBTAP00000015797 | ENSBTAP00000000282 | Activin receptor type-1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May also bind activin; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.988 |
| ACVR1 | BMPR1B | ENSBTAP00000015797 | ENSBTAP00000060109 | Activin receptor type-1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May also bind activin; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.975 |
| ACVR1 | BMPR2 | ENSBTAP00000015797 | ENSBTAP00000058820 | Activin receptor type-1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May also bind activin; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.992 |
| ACVR1 | GDF2 | ENSBTAP00000015797 | ENSBTAP00000006587 | Activin receptor type-1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May also bind activin; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Growth differentiation factor 2. | 0.858 |
| ACVR1 | SMAD5 | ENSBTAP00000015797 | ENSBTAP00000064729 | Activin receptor type-1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May also bind activin; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.987 |
| ACVR1 | SMAD9 | ENSBTAP00000015797 | ENSBTAP00000009982 | Activin receptor type-1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May also bind activin; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.977 |
| BMP10 | ACVR1 | ENSBTAP00000001312 | ENSBTAP00000015797 | Bone morphogenetic protein 10. | Activin receptor type-1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May also bind activin; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.878 |
| BMP10 | BMP2 | ENSBTAP00000001312 | ENSBTAP00000006739 | Bone morphogenetic protein 10. | Bone morphogenetic protein 2. | 0.451 |
| BMP10 | BMP4 | ENSBTAP00000001312 | ENSBTAP00000004992 | Bone morphogenetic protein 10. | Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). | 0.511 |
| BMP10 | BMP7 | ENSBTAP00000001312 | ENSBTAP00000053246 | Bone morphogenetic protein 10. | Bone morphogenetic protein 7. | 0.526 |
| BMP10 | BMPR1A | ENSBTAP00000001312 | ENSBTAP00000000282 | Bone morphogenetic protein 10. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.847 |
| BMP10 | BMPR1B | ENSBTAP00000001312 | ENSBTAP00000060109 | Bone morphogenetic protein 10. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.702 |
| BMP10 | BMPR2 | ENSBTAP00000001312 | ENSBTAP00000058820 | Bone morphogenetic protein 10. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.990 |
| BMP10 | GDF2 | ENSBTAP00000001312 | ENSBTAP00000006587 | Bone morphogenetic protein 10. | Growth differentiation factor 2. | 0.764 |
| BMP10 | SMAD5 | ENSBTAP00000001312 | ENSBTAP00000064729 | Bone morphogenetic protein 10. | Mothers against decapentaplegic homolog. | 0.612 |
| BMP10 | SMAD9 | ENSBTAP00000001312 | ENSBTAP00000009982 | Bone morphogenetic protein 10. | Mothers against decapentaplegic homolog. | 0.490 |
