MECOM protein (Bos taurus) - STRING interaction network

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Your Current Organism:

Bos taurus

NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAMKMT	ENSBTAP00000066362	ENSBTAP00000043450	ENSBTAP00000066362	Calmodulin-lysine N-methyltransferase.	Uncharacterized protein.	0.766
CAMKMT	MECOM	ENSBTAP00000043450	ENSBTAP00000059674	Calmodulin-lysine N-methyltransferase.	MDS1 and EVI1 complex locus.	0.876
CAMKMT	PLOD2	ENSBTAP00000043450	ENSBTAP00000031895	Calmodulin-lysine N-methyltransferase.	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2.	0.914
CAMKMT	PLOD3	ENSBTAP00000043450	ENSBTAP00000000447	Calmodulin-lysine N-methyltransferase.	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3.	0.914
CTBP1	CTBP2	ENSBTAP00000063352	ENSBTAP00000004405	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.	0.992
CTBP1	ENSBTAP00000066362	ENSBTAP00000063352	ENSBTAP00000066362	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein.	0.705
CTBP1	HDAC1	ENSBTAP00000063352	ENSBTAP00000070647	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...]	0.985
CTBP1	HDAC2	ENSBTAP00000063352	ENSBTAP00000059606	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.970
CTBP1	MECOM	ENSBTAP00000063352	ENSBTAP00000059674	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	MDS1 and EVI1 complex locus.	0.958
CTBP1	RUNX1	ENSBTAP00000063352	ENSBTAP00000006224	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.925
CTBP2	CTBP1	ENSBTAP00000004405	ENSBTAP00000063352	C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.992
CTBP2	ENSBTAP00000066362	ENSBTAP00000004405	ENSBTAP00000066362	C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.	Uncharacterized protein.	0.705
CTBP2	HDAC1	ENSBTAP00000004405	ENSBTAP00000070647	C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...]	0.983
CTBP2	HDAC2	ENSBTAP00000004405	ENSBTAP00000059606	C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.974
CTBP2	MECOM	ENSBTAP00000004405	ENSBTAP00000059674	C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.	MDS1 and EVI1 complex locus.	0.960
CTBP2	RUNX1	ENSBTAP00000004405	ENSBTAP00000006224	C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.925
ENSBTAP00000066362	CAMKMT	ENSBTAP00000066362	ENSBTAP00000043450	Uncharacterized protein.	Calmodulin-lysine N-methyltransferase.	0.766
ENSBTAP00000066362	CTBP1	ENSBTAP00000066362	ENSBTAP00000063352	Uncharacterized protein.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.705
ENSBTAP00000066362	CTBP2	ENSBTAP00000066362	ENSBTAP00000004405	Uncharacterized protein.	C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.	0.705
ENSBTAP00000066362	HDAC1	ENSBTAP00000066362	ENSBTAP00000070647	Uncharacterized protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...]	0.540

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