BDKRB2 protein (Bos taurus) - STRING interaction network

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Your Current Organism:

Bos taurus

NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGT	BDKRB2	ENSBTAP00000057860	ENSBTAP00000060552	Angiotensinogen; Belongs to the serpin family.	Bradykinin receptor B2.	0.974
AGT	EDN1	ENSBTAP00000057860	ENSBTAP00000010649	Angiotensinogen; Belongs to the serpin family.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.794
AGT	EDNRB	ENSBTAP00000057860	ENSBTAP00000006979	Angiotensinogen; Belongs to the serpin family.	Endothelin receptor type B; Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.	0.970
AGT	F2	ENSBTAP00000057860	ENSBTAP00000009406	Angiotensinogen; Belongs to the serpin family.	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity); Belongs to the peptidase S1 family.	0.738
AGT	GNA11	ENSBTAP00000057860	ENSBTAP00000050620	Angiotensinogen; Belongs to the serpin family.	Guanine nucleotide-binding protein subunit alpha-11; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	0.571
AGT	GNA14	ENSBTAP00000057860	ENSBTAP00000058528	Angiotensinogen; Belongs to the serpin family.	Guanine nucleotide-binding protein subunit alpha-14; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems; Belongs to the G-alpha family. G(q) subfamily.	0.571
AGT	GNAQ	ENSBTAP00000057860	ENSBTAP00000016160	Angiotensinogen; Belongs to the serpin family.	G protein subunit alpha q.	0.571
AGT	KNG1	ENSBTAP00000057860	ENSBTAP00000048995	Angiotensinogen; Belongs to the serpin family.	Kininogen-1 heavy chain; (1) Kininogens are inhibitors of thiol proteases; (2) HMW- kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of [...]	0.761
BDKRB2	AGT	ENSBTAP00000060552	ENSBTAP00000057860	Bradykinin receptor B2.	Angiotensinogen; Belongs to the serpin family.	0.974
BDKRB2	CHRM4	ENSBTAP00000060552	ENSBTAP00000045040	Bradykinin receptor B2.	Muscarinic acetylcholine receptor M4; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase. May couple to multiple functional responses in cell lines; Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM4 sub-subfamily.	0.886
BDKRB2	EDN1	ENSBTAP00000060552	ENSBTAP00000010649	Bradykinin receptor B2.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.962
BDKRB2	EDNRB	ENSBTAP00000060552	ENSBTAP00000006979	Bradykinin receptor B2.	Endothelin receptor type B; Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.	0.911
BDKRB2	F2	ENSBTAP00000060552	ENSBTAP00000009406	Bradykinin receptor B2.	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity); Belongs to the peptidase S1 family.	0.957
BDKRB2	GNA11	ENSBTAP00000060552	ENSBTAP00000050620	Bradykinin receptor B2.	Guanine nucleotide-binding protein subunit alpha-11; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	0.969
BDKRB2	GNA14	ENSBTAP00000060552	ENSBTAP00000058528	Bradykinin receptor B2.	Guanine nucleotide-binding protein subunit alpha-14; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems; Belongs to the G-alpha family. G(q) subfamily.	0.913
BDKRB2	GNA15	ENSBTAP00000060552	ENSBTAP00000026624	Bradykinin receptor B2.	G protein subunit alpha 15.	0.905
BDKRB2	GNAQ	ENSBTAP00000060552	ENSBTAP00000016160	Bradykinin receptor B2.	G protein subunit alpha q.	0.965
BDKRB2	KNG1	ENSBTAP00000060552	ENSBTAP00000048995	Bradykinin receptor B2.	Kininogen-1 heavy chain; (1) Kininogens are inhibitors of thiol proteases; (2) HMW- kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of [...]	0.997
CHRM4	BDKRB2	ENSBTAP00000045040	ENSBTAP00000060552	Muscarinic acetylcholine receptor M4; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase. May couple to multiple functional responses in cell lines; Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM4 sub-subfamily.	Bradykinin receptor B2.	0.886
CHRM4	EDN1	ENSBTAP00000045040	ENSBTAP00000010649	Muscarinic acetylcholine receptor M4; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase. May couple to multiple functional responses in cell lines; Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM4 sub-subfamily.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.787

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