STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAP1ArfGAP with dual PH domains 1. (532 aa)    
Predicted Functional Partners:
PSMG3
Proteasome assembly chaperone 3; Chaperone protein which promotes assembly of the 20S proteasome. May cooperate with PSMG1-PSMG2 heterodimers to orchestrate the correct assembly of proteasomes; Belongs to the PSMG3 family.
      
 0.618
KIF13B
Kinesin family member 13B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 
 0.615
KIF13A
Kinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 
 0.615
AGFG2
ArfGAP with FG repeats 2.
   
 
0.615
ARF1
ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form [...]
   
 
 0.534
ARF6
ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.490
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2.
      
0.485
GPR146
G protein-coupled receptor 146.
      
 0.483
COX19
Cytochrome c oxidase assembly protein COX19; Required for the transduction of an SCO1-dependent redox signal from the mitochondrion to ATP7A to regulate cellular copper homeostasis. May be required for the assembly of mitochondrial cytochrome c oxidase (By similarity).
      
 0.481
ENSBTAP00000067140
Uncharacterized protein.
    
 
 0.472
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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