Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BMT2 | SLC39A9 | ENSBTAP00000010002 | ENSBTAP00000023676 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | Solute carrier family 39 member 9. | 0.693 |
| BMT2 | TM4SF5 | ENSBTAP00000010002 | ENSBTAP00000062342 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | Transmembrane 4 L6 family member 5; Acts as a lysosomal membrane arginine sensor (By similarity). Forms a complex with MTOR and SLC38A9 on lysosomal membranes in an arginine-regulated manner, leading to arginine efflux which enables the activation of mTORC1 which subsequently leads to RPS6KB1 and EIF4EBP1 phosphorylations (By similarity). Facilitates cell cycle G1/S phase progression and the translocation of the CDK4-CCND1 complex into the nucleus (By similarity). CDKN1B and RHOA/ROCK signaling activity are involved in TM4SF5-mediated acceleration of G1/S phase progression (By similarity). | 0.638 |
| CD82 | G5E5G7_BOVIN | ENSBTAP00000007723 | ENSBTAP00000018111 | Tetraspanin. | Tetraspanin. | 0.778 |
| CD82 | TM4SF5 | ENSBTAP00000007723 | ENSBTAP00000062342 | Tetraspanin. | Transmembrane 4 L6 family member 5; Acts as a lysosomal membrane arginine sensor (By similarity). Forms a complex with MTOR and SLC38A9 on lysosomal membranes in an arginine-regulated manner, leading to arginine efflux which enables the activation of mTORC1 which subsequently leads to RPS6KB1 and EIF4EBP1 phosphorylations (By similarity). Facilitates cell cycle G1/S phase progression and the translocation of the CDK4-CCND1 complex into the nucleus (By similarity). CDKN1B and RHOA/ROCK signaling activity are involved in TM4SF5-mediated acceleration of G1/S phase progression (By similarity). | 0.569 |
| CD82 | TSPAN10 | ENSBTAP00000007723 | ENSBTAP00000052614 | Tetraspanin. | Tetraspanin. | 0.678 |
| CD82 | TSPAN14 | ENSBTAP00000007723 | ENSBTAP00000067827 | Tetraspanin. | Tetraspanin. | 0.668 |
| CD82 | TSPAN19 | ENSBTAP00000007723 | ENSBTAP00000055487 | Tetraspanin. | Tetraspanin. | 0.655 |
| CD82 | TSPAN4 | ENSBTAP00000007723 | ENSBTAP00000025806 | Tetraspanin. | Tetraspanin. | 0.661 |
| CD82 | TSPAN7 | ENSBTAP00000007723 | ENSBTAP00000011802 | Tetraspanin. | Tetraspanin. | 0.722 |
| G5E5G7_BOVIN | CD82 | ENSBTAP00000018111 | ENSBTAP00000007723 | Tetraspanin. | Tetraspanin. | 0.778 |
| G5E5G7_BOVIN | TM4SF5 | ENSBTAP00000018111 | ENSBTAP00000062342 | Tetraspanin. | Transmembrane 4 L6 family member 5; Acts as a lysosomal membrane arginine sensor (By similarity). Forms a complex with MTOR and SLC38A9 on lysosomal membranes in an arginine-regulated manner, leading to arginine efflux which enables the activation of mTORC1 which subsequently leads to RPS6KB1 and EIF4EBP1 phosphorylations (By similarity). Facilitates cell cycle G1/S phase progression and the translocation of the CDK4-CCND1 complex into the nucleus (By similarity). CDKN1B and RHOA/ROCK signaling activity are involved in TM4SF5-mediated acceleration of G1/S phase progression (By similarity). | 0.568 |
| G5E5G7_BOVIN | TSPAN10 | ENSBTAP00000018111 | ENSBTAP00000052614 | Tetraspanin. | Tetraspanin. | 0.873 |
| G5E5G7_BOVIN | TSPAN14 | ENSBTAP00000018111 | ENSBTAP00000067827 | Tetraspanin. | Tetraspanin. | 0.873 |
| G5E5G7_BOVIN | TSPAN19 | ENSBTAP00000018111 | ENSBTAP00000055487 | Tetraspanin. | Tetraspanin. | 0.873 |
| G5E5G7_BOVIN | TSPAN4 | ENSBTAP00000018111 | ENSBTAP00000025806 | Tetraspanin. | Tetraspanin. | 0.874 |
| G5E5G7_BOVIN | TSPAN7 | ENSBTAP00000018111 | ENSBTAP00000011802 | Tetraspanin. | Tetraspanin. | 0.873 |
| SLC39A9 | BMT2 | ENSBTAP00000023676 | ENSBTAP00000010002 | Solute carrier family 39 member 9. | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | 0.693 |
| SLC39A9 | TM4SF5 | ENSBTAP00000023676 | ENSBTAP00000062342 | Solute carrier family 39 member 9. | Transmembrane 4 L6 family member 5; Acts as a lysosomal membrane arginine sensor (By similarity). Forms a complex with MTOR and SLC38A9 on lysosomal membranes in an arginine-regulated manner, leading to arginine efflux which enables the activation of mTORC1 which subsequently leads to RPS6KB1 and EIF4EBP1 phosphorylations (By similarity). Facilitates cell cycle G1/S phase progression and the translocation of the CDK4-CCND1 complex into the nucleus (By similarity). CDKN1B and RHOA/ROCK signaling activity are involved in TM4SF5-mediated acceleration of G1/S phase progression (By similarity). | 0.599 |
| TM4SF20 | TM4SF5 | ENSBTAP00000028426 | ENSBTAP00000062342 | Transmembrane 4 L6 family member 20; Polytopic transmembrane protein. Inhibits regulated intramembrane proteolysis (RIP) of CREB3L1, inhibiting its activation and the induction of collagen synthesis. In response to ceramide, which alters TM4SF20 membrane topology, stimulates RIP activation of CREB3L1. Ceramide reverses the direction through which transmembrane helices are translocated into the endoplasmic reticulum membrane during translation of TM4SF20, this mechanism is called 'regulated alternative translocation' (RAT) and regulates the function of the transmembrane protein. | Transmembrane 4 L6 family member 5; Acts as a lysosomal membrane arginine sensor (By similarity). Forms a complex with MTOR and SLC38A9 on lysosomal membranes in an arginine-regulated manner, leading to arginine efflux which enables the activation of mTORC1 which subsequently leads to RPS6KB1 and EIF4EBP1 phosphorylations (By similarity). Facilitates cell cycle G1/S phase progression and the translocation of the CDK4-CCND1 complex into the nucleus (By similarity). CDKN1B and RHOA/ROCK signaling activity are involved in TM4SF5-mediated acceleration of G1/S phase progression (By similarity). | 0.664 |
| TM4SF5 | BMT2 | ENSBTAP00000062342 | ENSBTAP00000010002 | Transmembrane 4 L6 family member 5; Acts as a lysosomal membrane arginine sensor (By similarity). Forms a complex with MTOR and SLC38A9 on lysosomal membranes in an arginine-regulated manner, leading to arginine efflux which enables the activation of mTORC1 which subsequently leads to RPS6KB1 and EIF4EBP1 phosphorylations (By similarity). Facilitates cell cycle G1/S phase progression and the translocation of the CDK4-CCND1 complex into the nucleus (By similarity). CDKN1B and RHOA/ROCK signaling activity are involved in TM4SF5-mediated acceleration of G1/S phase progression (By similarity). | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | 0.638 |
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