| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATF1 | CREB1 | ENSBTAP00000058370 | ENSBTAP00000007201 | Cyclic AMP-dependent transcription factor ATF-1; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Mediates PKA-induced stimulation of CRE- reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation (By similarity); Belongs to the bZIP family. ATF subfamily. | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | 0.998 |
| ATF1 | CRTC1 | ENSBTAP00000058370 | ENSBTAP00000062485 | Cyclic AMP-dependent transcription factor ATF-1; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Mediates PKA-induced stimulation of CRE- reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation (By similarity); Belongs to the bZIP family. ATF subfamily. | CREB regulated transcription coactivator 1. | 0.577 |
| ATF1 | CRTC2 | ENSBTAP00000058370 | ENSBTAP00000050880 | Cyclic AMP-dependent transcription factor ATF-1; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Mediates PKA-induced stimulation of CRE- reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation (By similarity); Belongs to the bZIP family. ATF subfamily. | CREB-regulated transcription coactivator 2; Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mit [...] | 0.821 |
| ATF1 | CRTC3 | ENSBTAP00000058370 | ENSBTAP00000014501 | Cyclic AMP-dependent transcription factor ATF-1; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Mediates PKA-induced stimulation of CRE- reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation (By similarity); Belongs to the bZIP family. ATF subfamily. | CREB regulated transcription coactivator 3. | 0.771 |
| ATF1 | ENSBTAP00000057622 | ENSBTAP00000058370 | ENSBTAP00000057622 | Cyclic AMP-dependent transcription factor ATF-1; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Mediates PKA-induced stimulation of CRE- reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation (By similarity); Belongs to the bZIP family. ATF subfamily. | TORC_N domain-containing protein. | 0.771 |
| CRCT1 | CRTC1 | ENSBTAP00000011465 | ENSBTAP00000062485 | Cysteine-rich C-terminal 1. | CREB regulated transcription coactivator 1. | 0.602 |
| CREB1 | ATF1 | ENSBTAP00000007201 | ENSBTAP00000058370 | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | Cyclic AMP-dependent transcription factor ATF-1; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Mediates PKA-induced stimulation of CRE- reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation (By similarity); Belongs to the bZIP family. ATF subfamily. | 0.998 |
| CREB1 | CRTC1 | ENSBTAP00000007201 | ENSBTAP00000062485 | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | CREB regulated transcription coactivator 1. | 0.810 |
| CREB1 | CRTC2 | ENSBTAP00000007201 | ENSBTAP00000050880 | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | CREB-regulated transcription coactivator 2; Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mit [...] | 0.987 |
| CREB1 | CRTC3 | ENSBTAP00000007201 | ENSBTAP00000014501 | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | CREB regulated transcription coactivator 3. | 0.923 |
| CREB1 | ENSBTAP00000057622 | ENSBTAP00000007201 | ENSBTAP00000057622 | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | TORC_N domain-containing protein. | 0.947 |
| CREB1 | SIK2 | ENSBTAP00000007201 | ENSBTAP00000027019 | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | Salt inducible kinase 2. | 0.596 |
| CRTC1 | ATF1 | ENSBTAP00000062485 | ENSBTAP00000058370 | CREB regulated transcription coactivator 1. | Cyclic AMP-dependent transcription factor ATF-1; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Mediates PKA-induced stimulation of CRE- reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation (By similarity); Belongs to the bZIP family. ATF subfamily. | 0.577 |
| CRTC1 | CRCT1 | ENSBTAP00000062485 | ENSBTAP00000011465 | CREB regulated transcription coactivator 1. | Cysteine-rich C-terminal 1. | 0.602 |
| CRTC1 | CREB1 | ENSBTAP00000062485 | ENSBTAP00000007201 | CREB regulated transcription coactivator 1. | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | 0.810 |
| CRTC1 | CRTC2 | ENSBTAP00000062485 | ENSBTAP00000050880 | CREB regulated transcription coactivator 1. | CREB-regulated transcription coactivator 2; Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mit [...] | 0.813 |
| CRTC1 | CRTC3 | ENSBTAP00000062485 | ENSBTAP00000014501 | CREB regulated transcription coactivator 1. | CREB regulated transcription coactivator 3. | 0.930 |
| CRTC1 | ENSBTAP00000057622 | ENSBTAP00000062485 | ENSBTAP00000057622 | CREB regulated transcription coactivator 1. | TORC_N domain-containing protein. | 0.775 |
| CRTC1 | ENSBTAP00000064310 | ENSBTAP00000062485 | ENSBTAP00000064310 | CREB regulated transcription coactivator 1. | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. | 0.578 |
| CRTC1 | OGT | ENSBTAP00000062485 | ENSBTAP00000042834 | CREB regulated transcription coactivator 1. | TPR_REGION domain-containing protein. | 0.569 |
