| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CASK | LIN7C | ENSBTAP00000062140 | ENSBTAP00000001914 | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. | Protein lin-7 homolog C; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may funct [...] | 0.913 |
| CASK | PPFIA2 | ENSBTAP00000062140 | ENSBTAP00000065599 | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. | PTPRF interacting protein alpha 2. | 0.774 |
| CASK | PPFIA3 | ENSBTAP00000062140 | ENSBTAP00000003696 | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. | PTPRF interacting protein alpha 3. | 0.757 |
| CASK | RAB3A | ENSBTAP00000062140 | ENSBTAP00000002783 | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. | Ras-related protein Rab-3A; Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane (By similarity). Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane (By similarity). Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed (By simi [...] | 0.585 |
| ERC1 | PPFIA2 | ENSBTAP00000071004 | ENSBTAP00000065599 | ELKS/RAB6-interacting/CAST family member 1. | PTPRF interacting protein alpha 2. | 0.754 |
| ERC1 | PPFIA3 | ENSBTAP00000071004 | ENSBTAP00000003696 | ELKS/RAB6-interacting/CAST family member 1. | PTPRF interacting protein alpha 3. | 0.694 |
| FCHSD1 | FNBP4 | ENSBTAP00000021194 | ENSBTAP00000027858 | Uncharacterized protein. | Formin binding protein 4. | 0.728 |
| FCHSD1 | PPFIA2 | ENSBTAP00000021194 | ENSBTAP00000065599 | Uncharacterized protein. | PTPRF interacting protein alpha 2. | 0.719 |
| FNBP4 | FCHSD1 | ENSBTAP00000027858 | ENSBTAP00000021194 | Formin binding protein 4. | Uncharacterized protein. | 0.728 |
| FNBP4 | PPFIA2 | ENSBTAP00000027858 | ENSBTAP00000065599 | Formin binding protein 4. | PTPRF interacting protein alpha 2. | 0.701 |
| LIN7C | CASK | ENSBTAP00000001914 | ENSBTAP00000062140 | Protein lin-7 homolog C; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may funct [...] | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. | 0.913 |
| LIN7C | PPFIA2 | ENSBTAP00000001914 | ENSBTAP00000065599 | Protein lin-7 homolog C; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may funct [...] | PTPRF interacting protein alpha 2. | 0.735 |
| LIN7C | PPFIA3 | ENSBTAP00000001914 | ENSBTAP00000003696 | Protein lin-7 homolog C; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may funct [...] | PTPRF interacting protein alpha 3. | 0.717 |
| LIN7C | RAB3A | ENSBTAP00000001914 | ENSBTAP00000002783 | Protein lin-7 homolog C; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may funct [...] | Ras-related protein Rab-3A; Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane (By similarity). Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane (By similarity). Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed (By simi [...] | 0.619 |
| PHIP | PPFIA2 | ENSBTAP00000034268 | ENSBTAP00000065599 | Pleckstrin homology domain interacting protein. | PTPRF interacting protein alpha 2. | 0.715 |
| PPFIA2 | CASK | ENSBTAP00000065599 | ENSBTAP00000062140 | PTPRF interacting protein alpha 2. | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. | 0.774 |
| PPFIA2 | ERC1 | ENSBTAP00000065599 | ENSBTAP00000071004 | PTPRF interacting protein alpha 2. | ELKS/RAB6-interacting/CAST family member 1. | 0.754 |
| PPFIA2 | FCHSD1 | ENSBTAP00000065599 | ENSBTAP00000021194 | PTPRF interacting protein alpha 2. | Uncharacterized protein. | 0.719 |
| PPFIA2 | FNBP4 | ENSBTAP00000065599 | ENSBTAP00000027858 | PTPRF interacting protein alpha 2. | Formin binding protein 4. | 0.701 |
| PPFIA2 | LIN7C | ENSBTAP00000065599 | ENSBTAP00000001914 | PTPRF interacting protein alpha 2. | Protein lin-7 homolog C; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may funct [...] | 0.735 |
