STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYYR1Uncharacterized protein. (405 aa)    
Predicted Functional Partners:
SLC4A11
Solute carrier family 4 member 11.
      
 0.854
COL8A2
Collagen type VIII alpha 2 chain.
   
  
 0.810
GPC4
Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
      
 0.668
CLDN14
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.628
ZP4
Processed zona pellucida sperm-binding protein 4; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor; Belongs to the ZP domain family. ZPB subfamily.
      
 0.626
CD200
CD200 molecule.
      
 0.603
CLEC14A
C-type lectin domain family 14, member A.
   
  
 0.590
KRT3
Keratin 3; Belongs to the intermediate filament family.
      
 0.572
CLRN1
Clarin 1.
      
 0.570
HTR1D
5-hydroxytryptamine receptor 1D.
      
 0.569
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.