STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATP10DPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1432 aa)    
Predicted Functional Partners:
TMEM30C
Cell cycle control protein 50C.
   
 
 0.852
TMEM30A
Cell cycle control protein 50A; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. [...]
   
 0.758
TMEM30B
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
   
 0.585
VWA2
Von Willebrand factor A domain containing 2.
    
 
 0.583
STPG1
O(6)-methylguanine-induced apoptosis 2; May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine; Belongs to the STPG1 family.
      
 0.576
ZSCAN31
Zinc finger and SCAN domain containing 31.
    
 
 0.571
PGBD1
SCAN box domain-containing protein.
    
 
 0.571
MAPRE3
Microtubule-associated protein, RP/EB family, member 3.
      
 0.569
ZSCAN26
Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation.
    
 
 0.567
TSSK4
Testis specific serine kinase 4; Belongs to the protein kinase superfamily.
    
 
 0.565
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.