STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRG3-2PRG3 protein. (218 aa)    
Predicted Functional Partners:
PTGR1
Prostaglandin reductase 1; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha. Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4 (By similarity).
      
 0.689
E1BCU0_BOVIN
Ig-like domain-containing protein.
      
 0.664
LOC100296565
Ig-like domain-containing protein.
      
 0.664
LOC786717
Ig-like domain-containing protein.
      
 0.664
NRDE2
NRDE-2, necessary for RNA interference, domain containing.
      
 0.592
PAPPA
Pappalysin 1.
    
 
 0.592
HBM
Hemoglobin subunit mu; Belongs to the globin family.
      
 0.578
IPCEF1
Interaction protein for cytohesin exchange factors 1.
      
 0.576
SHCBP1L
SHC binding and spindle associated 1 like.
      
 0.559
IGFLR1
IGF-like family receptor 1; Probable cell membrane receptor for the IGF-like family protein IGFL.
    
 
 0.553
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.