STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USP32Ubiquitin specific peptidase 32; Belongs to the peptidase C19 family. (1631 aa)    
Predicted Functional Partners:
FAM162B
Protein FAM162B.
    
 
 0.837
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2.
   
 
 0.713
YPEL5
Protein yippee-like 5; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (By similarity). Required for normal cell proliferation (By similarity).
   
  
 0.697
APPBP2
Amyloid beta precursor protein binding protein 2.
 
 
  
 0.663
BCAS3
BCAS3 microtubule associated cell migration factor.
      
 0.650
GPR162
G protein-coupled receptor 162.
    
 
 0.636
SCFD1
Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family.
      
 0.622
TRIM45
Tripartite motif-containing protein 45; May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway; Belongs to the TRIM/RBCC family.
    
 
 0.602
DHX40
DEAH (Asp-Glu-Ala-His) box polypeptide 40.
   
 
 0.601
WDR7
WD repeat domain 7.
   
  
 0.595
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.