STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB13Beta-defensin 11; Has bactericidal activity. Active against E.coli ML35 and S.aureus 502A. (60 aa)    
Predicted Functional Partners:
CAMP
Cathelicidin-7; Exerts a potent antimicrobial activity.
   
  
 0.719
CATHL1
Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms; Belongs to the cathelicidin family.
   
  
 0.701
CATHL2
Cathelicidin-2; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms.
   
  
 0.691
CATHL5
Cathelicidin-5; Exerts a potent antimicrobial activity against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, and fungi; Belongs to the cathelicidin family.
   
  
 0.644
CATHL6
Cathelicidin-6; Exerts a potent antimicrobial activity against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, and fungi; Belongs to the cathelicidin family.
   
  
 0.631
LOC112443481
Cathelicidin-4; Potent microbicidal activity; active against S.aureus and E.coli; Belongs to the cathelicidin family.
   
  
 0.577
CATHL4
Cathelicidin 4.
   
  
 0.577
LEAP2
Liver-expressed antimicrobial peptide 2; Has an antimicrobial activity; Belongs to the LEAP2 family.
      
 0.509
LOC789175
Beta-defensin 103B.
      
 0.414
LOC101905775
Sperm associated antigen 11 isoform E.
   
  
 0.401
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.