STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEGR1Uncharacterized protein. (354 aa)    
Predicted Functional Partners:
LOC781645
LOC781645 protein.
    
 
 0.750
SLC44A5
Solute carrier family 44 member 5; Belongs to the CTL (choline transporter-like) family.
      
 0.696
MTCH2
Mitochondrial carrier homolog 2; The substrate transported is not yet known. Induces mitochondrial depolarization (By similarity); Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.683
FAM227B
Uncharacterized protein.
      
 0.661
KCTD15
BTB/POZ domain-containing protein KCTD15; During embryonic development, interferes with neural crest formation. Inhibits AP2 transcriptional activity by interaction with its activation domain (By similarity).
      
 0.658
LRRIQ3
Leucine rich repeats and IQ motif containing 3.
    
 
 0.602
FPGT
Fucose-1-phosphate guanylyltransferase.
    
 
 0.586
GNPDA2
Glucosamine-6-phosphate isomerase 2.
      
 0.556
TMEM150B
Modulator of macroautophagy TMEM150B; Modulator of macroautophagy that causes accumulation of autophagosomes under basal conditions and enhances autophagic flux (By similarity). Represses cell death and promotes long-term clonogenic survival of cells grown in the absence of glucose in a macroautophagy- independent manner (By similarity). May have some role in extracellular matrix engulfment or growth factor receptor recycling, both of which can modulate cell survival (By similarity). Belongs to the DRAM/TMEM150 family.
   
  
 0.555
ST6GALNAC3
Uncharacterized protein; Belongs to the glycosyltransferase 29 family.
      
 0.547
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.