node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C17orf58 | CCDC115 | ENSBTAP00000059864 | ENSBTAP00000004187 | Chromosome 17 open reading frame 58. | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity). May be involved in Golgi homeostasis (By similarity). | 0.583 |
C17orf58 | FAM234B | ENSBTAP00000059864 | ENSBTAP00000019045 | Chromosome 17 open reading frame 58. | Family with sequence similarity 234 member B. | 0.652 |
C17orf58 | FAM91A1 | ENSBTAP00000059864 | ENSBTAP00000006615 | Chromosome 17 open reading frame 58. | Family with sequence similarity 91 member A1. | 0.655 |
C17orf58 | NKAIN3 | ENSBTAP00000059864 | ENSBTAP00000073493 | Chromosome 17 open reading frame 58. | Sodium/potassium transporting ATPase interacting 3. | 0.675 |
C17orf58 | PRELID2 | ENSBTAP00000059864 | ENSBTAP00000053263 | Chromosome 17 open reading frame 58. | PRELI domain containing 2. | 0.626 |
C17orf58 | PXYLP1 | ENSBTAP00000059864 | ENSBTAP00000060418 | Chromosome 17 open reading frame 58. | 2-phosphoxylose phosphatase 1; Belongs to the histidine acid phosphatase family. | 0.577 |
C17orf58 | STK32A | ENSBTAP00000059864 | ENSBTAP00000071007 | Chromosome 17 open reading frame 58. | Serine/threonine kinase 32A; Belongs to the protein kinase superfamily. | 0.576 |
C17orf58 | VXN | ENSBTAP00000059864 | ENSBTAP00000002838 | Chromosome 17 open reading frame 58. | Vexin; Required for neurogenesis in the neural plate and retina. Strongly cooperates with neural bHLH factors to promote neurogenesis. Belongs to the vexin family. | 0.668 |
CADPS2 | FSTL5 | ENSBTAP00000068752 | ENSBTAP00000055765 | RING finger protein 148. | Uncharacterized protein. | 0.513 |
CADPS2 | NKAIN3 | ENSBTAP00000068752 | ENSBTAP00000073493 | RING finger protein 148. | Sodium/potassium transporting ATPase interacting 3. | 0.663 |
CCDC115 | C17orf58 | ENSBTAP00000004187 | ENSBTAP00000059864 | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity). May be involved in Golgi homeostasis (By similarity). | Chromosome 17 open reading frame 58. | 0.583 |
CCDC115 | FAM234B | ENSBTAP00000004187 | ENSBTAP00000019045 | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity). May be involved in Golgi homeostasis (By similarity). | Family with sequence similarity 234 member B. | 0.581 |
CCDC115 | FAM91A1 | ENSBTAP00000004187 | ENSBTAP00000006615 | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity). May be involved in Golgi homeostasis (By similarity). | Family with sequence similarity 91 member A1. | 0.577 |
CCDC115 | NKAIN3 | ENSBTAP00000004187 | ENSBTAP00000073493 | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity). May be involved in Golgi homeostasis (By similarity). | Sodium/potassium transporting ATPase interacting 3. | 0.632 |
CCDC115 | PRELID2 | ENSBTAP00000004187 | ENSBTAP00000053263 | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity). May be involved in Golgi homeostasis (By similarity). | PRELI domain containing 2. | 0.578 |
CCDC115 | PXYLP1 | ENSBTAP00000004187 | ENSBTAP00000060418 | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity). May be involved in Golgi homeostasis (By similarity). | 2-phosphoxylose phosphatase 1; Belongs to the histidine acid phosphatase family. | 0.555 |
CCDC115 | STK32A | ENSBTAP00000004187 | ENSBTAP00000071007 | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity). May be involved in Golgi homeostasis (By similarity). | Serine/threonine kinase 32A; Belongs to the protein kinase superfamily. | 0.537 |
CCDC115 | VXN | ENSBTAP00000004187 | ENSBTAP00000002838 | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity). May be involved in Golgi homeostasis (By similarity). | Vexin; Required for neurogenesis in the neural plate and retina. Strongly cooperates with neural bHLH factors to promote neurogenesis. Belongs to the vexin family. | 0.620 |
FAM234B | C17orf58 | ENSBTAP00000019045 | ENSBTAP00000059864 | Family with sequence similarity 234 member B. | Chromosome 17 open reading frame 58. | 0.652 |
FAM234B | CCDC115 | ENSBTAP00000019045 | ENSBTAP00000004187 | Family with sequence similarity 234 member B. | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity). May be involved in Golgi homeostasis (By similarity). | 0.581 |