STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NKAIN3Sodium/potassium transporting ATPase interacting 3. (209 aa)    
Predicted Functional Partners:
FSTL5
Uncharacterized protein.
      
 0.817
VXN
Vexin; Required for neurogenesis in the neural plate and retina. Strongly cooperates with neural bHLH factors to promote neurogenesis. Belongs to the vexin family.
      
 0.686
C17orf58
Chromosome 17 open reading frame 58.
   
  
 0.675
FAM234B
Family with sequence similarity 234 member B.
      
 0.666
CADPS2
RING finger protein 148.
      
 0.663
FAM91A1
Family with sequence similarity 91 member A1.
      
 0.662
PRELID2
PRELI domain containing 2.
      
 0.662
STK32A
Serine/threonine kinase 32A; Belongs to the protein kinase superfamily.
   
  
 0.644
PXYLP1
2-phosphoxylose phosphatase 1; Belongs to the histidine acid phosphatase family.
      
 0.634
CCDC115
Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity). May be involved in Golgi homeostasis (By similarity).
      
 0.632
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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