Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KCNA4Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (659 aa)    
Predicted Functional Partners:
KCNAB3
Potassium voltage-gated channel subfamily A regulatory beta subunit 3.
   
 0.703
KCNAB2
Potassium voltage-gated channel subfamily A regulatory beta subunit 2.
   
 0.700
KCNH2
Potassium voltage-gated channel subfamily H member 2.
     
 0.685
SCN5A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
 
 0.681
KCNMA1-2
Uncharacterized protein.
   
  
 0.679
KCNMA1
Potassium calcium-activated channel subfamily M alpha 1.
   
  
 0.679
KCNAB1
Potassium voltage-gated channel subfamily A member regulatory beta subunit 1.
   
 0.678
CCDC73
Coiled-coil domain containing 73.
    
 
 0.672
KCNIP2
Potassium voltage-gated channel interacting protein 2.
   
 0.616
ENSCHIP00000000289
Uncharacterized protein.
   
  0.612
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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