Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF25Uncharacterized protein. (619 aa)    
Predicted Functional Partners:
PLA2G4A
Phospholipase A2.
   
 
 0.711
SLC26A10
Solute carrier family 26 member 10.
   
  
 0.663
ARHGEF37
Rho guanine nucleotide exchange factor 37.
     
 0.638
RSPRY1
Ring finger and SPRY domain containing 1.
      
 0.633
ARHGEF28
Rho guanine nucleotide exchange factor 28.
   
 
 0.619
MORN1
MORN repeat containing 1.
   
  
 0.605
RHOBTB3
Rho related BTB domain containing 3.
    
 0.600
PIP4K2C
Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma.
      
 0.595
ZNF579
Zinc finger protein 579.
    
 0.588
RXFP2
Relaxin family peptide receptor 2.
   
 
  0.574
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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